HBTRC Staff
HBTRC Brain Sections
HBTRC Facility
Harvard Brain Tissue Resource Center Home
Decrease Font Size Increase Font Size

Publications Derived From HBTRC Tissue Samples (2000-2013)

  1. Abdolmaleky HM, Cheng H-h, Russo A, Smith CL, Faraone SV, Wilcox M, Shafa R, Glatt SJ, Nguyen G, Ponte JF, Thiagalingam S, Tsuang MT.  Hypermethylation of the reelin  (RELN) promoter in the brain of schizophrenic patients:  A Preliminary Report.  Amer J Med Genetics, 134B:60-66 2005.
  2. Abdolmaleky HM, Cheng H-h, Faraone SV, Wilcox M, Glatt SJ, Fangming  G, Smith C,  Shafa R, Aeali B, Carnevale J, Pan H, Papageorgis P,  Ponte JF, Sivaraman V, Tsuang MT, Thiagalingam S.  Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Human Molecular Genetics, 15;21:3132-3134 2006.
  3. Abdolmaleky HM, Thiagalingam S.  Epigenetic Alterations of the Dopaminergic System in Major Psychiatric Disorders.  Accepted as a chapter of a book by Humana Press. 2007
  4. Abdolmaleky HM, Zhou J, Thiagalingam S.  Epigenetic modulation of reelin function in schizophrenia and bipolar disorder. Submitted as a book chapter.
  5. Adamec E, Chang HT, Stopa EG, Hedreen JC, Vonsattel JP.Tau protein expression in frontotemporal dementias. Neurosci Lett. 2001 Nov 23;315 (1-2):21-4.
  6. Akbarian S, Huang HS.  2006.  Molecular and cellular mechanisms of altered GAD1/GAD67 expression in schizophrenia and related disorders.  Brain Res Brain Res Rev 2006 Jun 5;[epub ahead of print].
  7. Amaral DG, Schumann CM and Nordahl CW.  Neuropathology of Autism. (to appear as an invited article in Trends in Neurosciences)
  8. Anthony SG, Schipper, HM, Taveres R, Hovanesian V, Cortez S, Stopa EG and Johanson CE.  Stress protein expression in the Alzheimer-diseased choroid plexus.  Journal of Alzheimer’s Disease 5:171-177, 2003.
  9. Araghi-Niknam M, Fatemi SH.  Levels of Bc12 and P53 are altered in superior frontal and cerebellum of autistic subjects.  Cell Mol Neurobiol 23:945-952, 2003.
  10. Armstrong D.  Rett Syndrome; The Challenge of the pathology.  Primary Psychiatry.  2003 10:59-63.
  11. Armstrong D.  Deguchi Kimiko, Antalffy B MECP2 in the Rett and the non-Rett brain.  J Child Neurology 2003;18:683-687.
  12. Armstrong D.  The relationship between MeCP2 expression and brain development, Brain and Development (in press). 
  13. Armstrong D.  Neuropathology of Rett Syndrome.  J Neuropathol Ex Neurol.  2005;20:747-752.
  14. Babu JR, Geetha T, Wooten, MW.  Sequestosome 1/p62 shuttles polybiquitinated tau for proteaseomal degradation.  J Neurochem  94:192-203, 2005
  15. Bäckman CM, Shan L, Zhang Y-J, Hoffer BJ, Leonard S, Troncoso JC, Vonsatel P and TomacAC. Gene expression patterns for GDNF and its receptors in the human putamenaffected by Parkinson’s disease: A real-time PCR study. Molecular and Cellular Endocrinology, 252: 160-166, 2006.
  16. Bäckman CM, Shan L, Zhang Y-J, Hoffer BJ, and Tomac AC.  Alterations inprodynorphin, proenkephalin and GAD67 mRNA levels in the aged human putamen: a correlation with Parkinson’s disease. Journal of Neuroscience Research, 85 (4): 798-804, 2007
  17. Balmer D, Arredondo J, Samaco RC, and LaSalle JM. 2002.  MECP2 mutations in Rett syndrome adversely affect lymphocyte growth but do not affect imprinted gene expression in blood or brain.  Hum. Genet., 110:545-552.
  18. Balmer D, Goldstine J, Rao YM, and LaSalle JM.  2003.  Elevated methyl CpG-binding protein 2 expression is acquired during postnatal human brain development and correlates with alternative polyadenylation. J. Mol.  Med.  81:61-68.
  19. Banwait S, Galvan V, Ataie M, Gorostiza O, Crippen D, Bredesen DE.  2006.  Asp664-cleaved forms of amyloid precursor protein in AD and non-diseased human brain.  Submitted for publication.
  20. Battista, N., Bari M., Tarditi A., Mariotti C., Bachoud-L´evi A.C., Zuccato C.,, Finazzi-Agrò A., Genitrini S., Peschanski M., Di Donato S., Cattaneo E., Maccarrone M. Severe deficiency of the fatty acid amide hydrolase (FAAH) activity segregates with the Huntington’s Disease mutation in peripheral lymphocytes. Neurobiology of Disease, in press.
  21. Benes, F.M.  2D Versus 3D Counting:  A Response to two commentaries:  One from Selemon, Goldman-Rakic and Rajkowska and the other from H. Uylings. Biological Psychiatry 2002.
  22. Benes, F.M., Tamminga, C.A.  Neurobiology of Schizophrenia.  In:  Psychiatry as a Neuroscience.  Lopez-Ibor, J.J., Gaebel, W., Maj, M., Sartorious, N.  (Eds.) John Wiley and Sons, Ltd. West Sussex, UK; 2002;  pp. 197-237.
  23. Benes, F.M., Berretta, S.  Defining the role of specific limbic circuitry in schizophrenia and bipolar disorder.  In:  The Postmortem Brain in Psychiatric Research.  Agam, G., Belmaker, R.H., Everall, I. (Eds.). Kluwer Academic Publishers.  2002: pp. 211-234.
  24. Benes, F.M. The neurobiology of schizophrenia.  In:  Textbook of Psychiatry.  Maj, M. (Ed.).  World Psychiatric Association Press.  2002: 81-105.
  25. Benes, F.M.  Is the GABA cell the final common pathway for the etiology and treatment of schizophrenia and bipolar disorder?  An Editorial.  Current Opinion in Psychiatry 2002; 15: 277-278.
  26. Benes, F.M., Walsh, J., Bhattacharyya, S., Sheth, A., Berretta, S.  DNA fragmentation is decreased in schizophrenia, but not bipolar disorder.  Archives of General Psychiatry 2003; 60:359-364.
  27. Benes, F.M. , Berretta, S.  The GABA cell in relation to schizophrenia and bipolar disorder.  In:  Handbook of Medical Psychiatry.  Soares, J.C., Gershon, S. (Eds.). Marcel Dekker, Inc. New York; 2003; pp. 277-295.
  28. Benes, F.M.  Schizophrenia: Amygdalar fiber alteration as etiology?  American Journal of Psychiatry 2003; 160: 1053. 
  29. Benes, F.M.  Why does psychosis develop during adolescence and early adulthood?  Editorial.  Current Opinion in Psychiatry 2003; 16: 317-319.
  30. Benes, F.M.  Invited Commentary:  A disturbance of late myelination as a trigger for Alzheimer’s Disease. Neurobiology of Aging 2003;  25:41-43.
  31. Benes, F.M.  Interactions of the dopamine, serotonin and GABA systems during childhood and adolescence. Influence of stress on the vulneribility for psychopathology.  In:  Neurodevelopmental Mechanisms of Psychopathology,” Cicchetti, D., Walker, E. (Eds.), Cambridge University Press, Cambridge; 2003; pp. 384-404.
  32. Benes, F.M.  Commentary.  A disturbance of late myelination as a trigger for Alzheimer’s disease.   Neurobiology of Aging 2003; In press.
  33. Benes, F.M.  The development of “mis-wired” limbic lobe circuitry in schizophrenia and bipolar disorder.  Psychiatric Times, January, 2004:  21:  48-49.
  34. Benes, F.M.  The development of “mis-wired” limbic lobe circuitry in schizophrenia and bipolar disorder.  In:  Neurodevelopment and Schizophrenia, Part III.  Pathophysiology.  Keshavan, M.S., Kennedy, J.L., Murray, R.J. (Eds.).  Cambridge University Press, Cambridge, U.K.; 2004;  pp. 295-309.
  35. Benes, F.M.  Editorial:  The role of apoptosis in neuronal pathology in schizophrenia and bipolar disorder.  Editorial. Current Opinion in Psychiatry 2004; 17:189-190.
  36. Benes, F.M.  Deserving the last great gift:  The ethics of brain banking.  Cerebrum 2004; In press.
  37. Benes, F.M.  Invited Editorial: Schizophrenia by Robert Freedman, M.D., for Neurology Watch, New England Journal of Medicine 2004, In press.
  38. Benes, F.M. Ethical issues in brain banking. Editorial. Current Opinion in Psychiatry; 2005; in press.
  39. Benes, F.M., Pare, Paré-Blagoev, J.  Brain Bases of Reading Disabilities, Chapter 7.  Mind, Brain, and Education in Reading Disorders, Fischer, K. and Bernstein, J. (Eds.). Cambridge University Press, Cambridge, U.K.; 2005; In press.
  40. Benes, F.M.  A Neurodevelopmental approach to the understanding of schizophrenia and other mental disorders.  In:  Developmental Psychopathology. Second Edition. Vol. II: Developmental Neuroscience.  Cicchetti, D. and Cohen, D.J. (Eds.);  John Wiley and Sons, Inc. 2006; pp. 216-258.
  41. Benes, F.M., Matzilevich, D., Burke, R., Walsh, J.P.  The expression of pro-apoptosis genes is increased in bipolar disorder, but not in schizophrenia.  Molecular Psychiatry 2006; 11:241-251
  42. Benes, F.M., Gisabella, B.  GABAergic dysfunction in schizophrenia and bipolar disorder.  Advances in Pharmacology 2006; 54:73-93.
  43.  Benes, F.M. The regulation of apoptosis in the limbic lobe of schizophrenia and bipolar disorder. Chapter 8, Section II In:  Functional Genomics and Proteomics in the Clinical Neurosciences.  Progress in Brain Research Series. Hemby. S.E., Bahn, S. (Eds.); Elsevier, Amsterdam; 2006; pp.153-172 .
  44. Benes, F.M., Cunningham, M.G., Berretta, S., Gisabella, B.  Course and pattern of cingulate pathology in schizophrenia.  In: Cingulate Neurobiology and Disease.  Second Edition.  Vogt, B.A. (Ed.); Chapt. 9; 2009; pp. 679-706 . 
  45. Benes FM, Lim B, Matzilevich D, Walsh JP, Subburaju S, Minns M.  Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars. Proc Natl Acad Sci U S A. 2007
  46. Benes, F.M.  Searching for unique endophenotypes for schizophrenia and bipolar disorder within neural circuits and their molecular regulatory mechanisms.  Schizophrenia Bulletin 2007:  In press.
  47. Berretta, S., Benes, F.M.  A rat model for neural circuitry abnormalities in schizophrenia.  Nature Protocols 2006; 1:  836-839. (doi:10.1038/nprot.2006.110)
  48. Berretta S, Pantazopolous H, Lange N (2007a) Neuron numbers and volume of  the amyggdala in subjects diagnosed with bipolar disorder or schizophrenia. Biological Psychiatry in press.
  49. Blatt, G.J. (2005) GABAergic cerebellar system in autism: A neuropathological and developmental perspective.  Int. Rev. Neurobiol. 71:167-178.
  50. Braunschweig D, Simcox T, Samaco RC, and LaSalle JM.  2004.  X-chromosome inactivation ratios affect wild-type MeCP2 expression within mosaic Rett syndrome and Mecp2-/+ mouse brain. Hum. Mol. Genet. 13:1275-1286.
  51. Burke, R.E., Walsh, J.P., Matzilevich, D., Benes, F.M.  Mapping of hippocampal gene clusters regulated by the amygdala to non-linkage sites for schizophrenia.  Molecular Psychiatry 2006:11:158-171.
  52. Buttner, E.A., Bhattacharyya, S., Walsh, J., Benes, F.M.  DNA fragmentation is increased in non-GABAergic neurons in bipolar disorder.  Schizophrenia Research 2007; 93: 33-41.
  53. Campbell DB, D’Oronzio R, Garbett K, Ebert PJ, Mirnics K, Levitt P, and Persico AM.  Disruption of Cerebral Cortex MET Signaling in Autism Spectrum Disorder.  Annals of Neurology, 2007.
  54. Cantuti-Castelvetri et al.  Expression and acitivity of antioxidans in the brain in progressive supranuclear palsy.  Brain Research 930:170181, 2002.
  55. Cantuti-Castelvetri et al.  Somatic Mictochondrial Mutations in Single Neurons and Glia.  Neurobiology of Aging, 26:1343-1355, 2005.
  56. Cantuti-Castelvetri et al.  Alpha-synuclein and Chaperones in Dementia with Lewy Bodies.  Journal of Neuropathology and Experimental Neurology, 2005.
  57. Cantuti-Castelvetri et al.  Effect of gender on nigral gene expression and Parkinson Disease,  Neurobiology of Disease, doi: 10.1016/j/nbd. 2007.02.009 in press
  58. Casanova MF, Buxhoeveden D, Gomez J. 2003 Disruption in the inhibitory architecture of the cell minicolumn: implications for autism. Neuroscientist Dec;9(6):496-507
  59. Casanova MF.  Neuropathological and genetic findings in autism: the significance of a putative minicolumnopathy. Neuroscientist. 2006 Oct;12(5):435-41.
  60. Casanova MF, van Kooten IA, Switala AE, van Engeland H, Heinsen H, Steinbusch HW, Hof PR, Trippe J, Stone J, Schmitz C.  2006.  Minicolumnar abnormalities in autism. Acta Neuropathol (Berl). 2006 Sep;112(3):287-303. Epub 2006 Jul 4.
  61. Cataldo AM, Peterhoff CM, Troncoso J, Gomez-Isla T, Hyman B, Nixon RA:  Abnormalities of neuronal endocytosis precede b-amyloid deposition, are enhanced by APOE genotype and differentiate subtypes of Alzheimer’s disease.  American J. Pathol., 2000, 157:277-286.
  62. Cataldo AM, Rebeck GW, Ghetti B, Hulette C, Lippa C, Van Broeckhoven C, Van Duijn C, Cras P, Bogdanovic N, Bird T, Peterhoff C, Nixon R;  Endocytic Disturbances Distinguish Among Subtypes of Alzheimer’s Disease and Related Disorders.  Ann of Neurol., 2001, 50:661-665.
  63. Cataldo AM, Petanceska S, Terio NB, Peterhoff CM, Troncoso J, Durham R, Mercken M, Mehta PD, Buxbaum J, Haroutunian V, Nixon RA.  Endosomal Pathology and Increased Ab Levels Coincide in Alzheimer’s Disease. Neurobiol Aging 2004; 25:1263-1272.
  64. Cataldo AM, Peterhoff CM, Schmidt SD, Duff K, Mathews PM, Beard M, Nixon RA.  Presenilin mutations in familial Alzheimer’s disease and transgenic mouse models accelerate neuronal lysosomal pathology.  J Neuropathol Exp Neurol 2004; 63:821-830.
  65. Chang HT, Cortez S, Vonsattel JP, Stopa EG, Schelper RL.  Familial frontotemporal dementia:  a report of three cases severe cerebral atrophy with rare inclusions that are negative for tau and synuclein, but positive for ubiquitin.  Acta Neuropathology (Berl).  2004 July; 108(1):10-6.  Epub 2004 Apr 2.
  66. Connor C, Siegmund KD, Campan M, Weisenberger DJ, Long TI, Jaenisch R, Laird P, Akbarian S.  DNA methylation is dynamically regulated in human cerebral cortex across the lifespan.  Submitted.
  67. Costa E, Grayson DR, Mitchell CP, Tremolizzo L, Veldic M, Guidotti A.  GABAergic cortical neuron chromatin as a putative target to treat shizophrenia vulnerability.  Critical Reviews in Neurobiology 15:121-142, 2003.
  68. Costa E, Done E, Grayson D, Ruzicka W, Simonini MV, Veldie M, Guidotti A.  Epigenetic targets in GABAergic neurons to treat schizophrenia. Advances in Pharmacology, 54:95-117, 2006.
  69. Costa E, Dong E, Grayson DR, Guidotti A, Ruzicka WB, Veldic M.  Reviewing the role ofDNA (cytosine-5) methyltransferase overexpression in the cortical GABAergic dysfunction associated with psychosis vulnerability. Epigenetics 2007 (in press).
  70. Courchesne E. 2004. Brain Development in autism: early overgrowth followed by premature arrest of growth.  Ment Retard Dev Disabil Res Rev.10(2):106-11.
  71. Brimacombe M, Pickett J, Pickett R. 2006.  Autism Post-Mortem Neuroinformatic Resource: The Autism Tissue Program (ATP) Informatics Portal. J Autism Dev Disord. 2006 Aug 24; [Epub ahead of print].
  72. Buxhoeveden, DB, Semendeferi, K, Buckwalter, J, Schenker, N, Switzer, R and E Courchesne.  2006.  Reduced minicolumns in the frontal cortex of patients with autism.  Neuropathology and Applied Neurobiology 32:1-9. 
  73. Cottrell BA, Galvan V, Banwait S, Gorostiza O, Lombardo CR, Williams T, Peel AL, Koo EH, aand Bredesen DE.  A pilot proteomic study of amyloid precursor protein interactors in Alzheimer’s disease.  Ann Neurol 2005; 58:277-289.
  74. Desplats PA, Kass KE, Gilmartin T, Stanwood GD, Head SH, Sutcliffe JG, Thomas EA. Selective deficits in the expression of striatal-enriched mRNAs in Huntington’s Disease.  J Neurochem 96:743-757, 2006.
  75. Desplats PA, Denny CA, Kass KE, Gilmartin T, Head SR, Sutcliffe JG, Seyfried TN, Thomas EA.  Glycolipid and ganglioside metabolism imbalances in Huntington’s Disease.  Neurobiology of Disease 7; 2007: 265-277.
  76. Donahue JE, Flaherty SL, Johanson CE, Duncan JA III, Silverberg GD, Tavares R, Yang W, Wu Q, Hovanesian V, Stopa EG, “RAGE, LRP-1, and amyloid-beta protein in Alzheimer’s disease,” Acta Neuropathol 2006 Oct; 112:405-15.
  77. Eyal A, Szargel R, Avraham E, Liani E, Haskin J, Rott R, and Engelender S.  Synphilin-1A: An aggregation-prone isoform of synphilin-1 that causes neuronal death and is present in aggregates from a-synucleinopathy patients.  PROCEEDINGS OF NATIONAL ACADEMY OF SCIENCES 103:5917-5922, 2006.
  78. Eberhart, C, Copeland, J & T Abel.  2006.  Brief Report: S6 Ribosomal Protein Phosphorylation in Autistic Frontal Cortex and Cerebellum: a Tissue Array Analysis.  J Autism Dev Disord. 36:1131-1136.
  79. Fatemi SH, Halt AR, Realmuto G, Jalali-Mousavi M.  Reduction in anti-apoptic protein Bcl-2 in autistic cerebellum.  NeuroReport 12:929-933, 2001.
  80. Fatemi SH, Stary J, Halt A, Realmuto G.  Dysregulation of Reelin and Bc1-2 in autistic cerebellum.  J Autism Disorders 31:529-535, 2001.
  81. Fatemi SH, Halt AR.  Altered levels of Bc12 and p53 Proteins in parietal cortex reflect deranged apoptic regulation in autism.   Synapse 42:281-284, 2001.
  82. Fatemi SH, Halt AR, Earle J, Kist DA, Thuras P, Realmuto G, Merz A.  A Reduced Purkinje cell size in cerebellum of patients with autism.  Cell Mol Neurobiol 22:171-175, 2002.
  83. Fatemi SH, Halt A, Stary JM, Kanodia R, Schulz SC, Realmuto GR.  Glutamic acid decarboxylase proteins of 65 and 67 kDa are reduced in parietal and cerebellar cortices of autistic subjects.  Biol Psychiatry 62:805-810, 2002.
  84. Fatemi SH, Merz A, Realmuto GR.  The roles of Reelin, Bc12 and serotonin in cerebellar pathology in autism.  J Develop Phys Dis 15:1-22, 2003.
  85. Fatemi SH, Snow AV, Stary JM, Ataghi-Niknam TJ, Lee, Brooks AL, Pearce DA.  Reelin signaling is impaired in autism.  Bio Psychiatry 57:777-787,2005.
  86. Floor E, Maples AM, Rankin CA, Yaganti VM, Shank SS, Nichols GS, O’Laughlin MO, Galeva NA, Williams TD.  A one-carbon modification of protein lysine associated with oxidative stress in human substantia nigra.  J Neurochem 97;504-514, 2006.
  87. Frenzel C. An update on autism brain tissue research; a summary of the 2002 IMFAR research findings.  Autism-Asperger’s Digest  Nov-Dec 2003.
  88. Frenzel, C.  Tantalizing Clues; Hope for the Future through the Autism Tissue Program. 2005.  Autism Spectrum Quarterly, Winter 2005.
  89. Galvan V, Cheng S, Lu D, Koo EH and Bredesen DE.  Caspase cleavage of members of the amyloid presursor family of proteins.  J Neurochem 2002; 82:283-294.
  90. Gene J. Blatt, G.J., Fitzgerald, C.M., Guptill, J.T., Booker, A.B., Kemper, T.L. & Bauman, M.L. (2001).  Density and distribution of hippocampal neurotransmitter receptors in autism: An autoradiographic study.  Journal of Autism and Developmental Disorders 31: 537-544.
  91. Gisabella, B., Bolshakov, V., Benes, F.M.  Regulation of synaptic plasticity in a schizophrenia model.  Proceedings of the National Academy of Sciences 2005; 102 (37): 13301-13306.
  92. Glatt SJ, Everall IP, Kremen WS, Corbeil J, Sasik R, Khanlou N, Han M, Liew CC, Tsuang MT.  Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia.  Proceedings of National Academy of Sciences 102:43;15533-15538, 2005
  93. Guidotti A, Auta J, Davis J, Dong E, Grayson DR, Veldie M, Zhang X, Costa E.  Psychopharm (Berl) 180:191-205, 2005
  94. Harper DG, Stopa EG, McKee AC, Satlin A, Harlan PC, Goldstein R, Volicer L.Differential circadian rhythm disturbances in men with Alzheimer disease and frontotemporal degeneration. Arch Gen Psychiatry. 2001 Apr;58(4):353-60
  95. Harper DG, Stopa EG, McKee AC, Satlin A, Fish D, Volicer L.  Dementia severity and Lewy boies affect circadian rhythm in Alzheimer disease.  Neurobiol Aging 2004 Jul(6):771-81
  96. Harper DG, Volicer L, Stopa EG, McKee AC, Nitta M, Satlin A.  Disturbance of endogenous circadian rhythm in aging and Alzheimer disease.  Am J Geriatr Psychiatry. 2005 May;13(5):359-68
  97. Heckers, S., Stone, D., Walsh, J., Shick, J., Koul, P., Benes, F.M.  Decreased expression of glutamatic acid decarboxylase (GAD)65 and 67 mRNA in bipolar disorder.  Archives of General Psychiatry 2002; 59: 521-529.
  98. Hemby, S.E., Sanchez, M.M. & Winslow, J.T.  (2001). Functional Genomics Approaches to A Primate Model of Autistic Symptomology. Journal of Autism and Developmental Disorders 31: 551-556.
  99. Hoffner G, Island M.-L and Djian P. Purification of neuronal inclusions of patients with Huntington disease reveals a broad range of N-terminal fragments of expanded huntingtin and insoluble polymers. J. Neurochem. 2005, 95:125-136.
  100. Hoffner G and P. Djian. Transglutaminase and diseases of the central nervous system. Frontiers Biosc. 2005, 10:3078-3092.
  101. Hogart A, Nagarajan RP, Patzel KA, Yasui DH, LaSalle JM.  2007.  15q11-13 GABAA receptor genes are normally biallelically expressed in brain yet are subject to epigenetic dysregulation in autism-spectrum disorders.  Hum. Mol. Genet. 16:691-703.
  102. Hong JJ, Loiselle CR, Yoon DY, Lee O, Becker KG, Singer HS.  Microarray analysis in Tourette syndrome portmortem putamen.  J Neurological Sciences 225;57-64, 2004
  103. Inoue H, Lin L, Lee X, Shao Z, Mendes S, Snodgrass-Belt P, Sweigard H, Engber T, Pepinsky B, Yanf L, Beal MF, Sha M, Isacson O.  Inhibition of the LRR-protein LINGO-1 enhances survival, structure and function of dopaminergic neurons in Parkinson’s disease models.  PROCEEDINGS OF NATIONAL ACADEMY OF SCIENCES, in press
  104. Ishikawa M, Mizukami K, Iwakiri M, Hidaka S, Asada T.  GABAA receptor gamma subunits in the prefrontal cortex of patients with schizophrenia and bipolar disorder. Neuroreport  2004;15(11):1809-1812
  105. Ishikawa M, Mizukami K, Iwakiri M, Hidaka S, Asada T.  Immunohistochemical and immunoblot study of GABA(A) alpha1 and beta2/3 subunits in the prefrontal cortex of subjects with schizophrenia and bipolar disorder.  Neurosci Research 2004; 50(1):77-84
  106. Ishikawa M, Mizukami K, Iwakiri M, Hidaka S, Asada T.  Immunohistochemical and immunoblot analysis of gamma-aminobutyric acid B receptor in the prefrontal cortex of subjects of  with schizophrenia and bipolar disorder.   Neurosci Letters 2005; 383 (3):272-277
  107. Ishikawa M, Mizukami K, Iwakiri M, Hidaka S, Asada T.  Immunohistochemical and immunoblot analysis of Dopamine and cyclic AMP-regulated phosphoprotein, relative molecular mass 32,000 (DARPP-32) in the prefrontal cortex of subjects with schizophrenia and bipolar disorder.  Progress in Neuropsychopharmacology  & Biological Psychiatry 2007 (in press).
  108. Ishikawa M, Mizukami K, Iwakiri M, Hidaka S, Sasaki M, Asada T.  GABAA   a1 and b2/3 subunits in the prefrontal cortex of subjects with schizophrenia and bipolar disorder.  XII World Congress of Psychiatry (Yokohama), August 24-29, 2002.
  109. Ishikawa M, Mizukami K,  Asada T.  Alterations in ubiquilin in the postmortem prefrontal cortex of subjects with schizophrenia.  36th Annual Meeting Society for Neuroscience (Atlanta), October, 2006
  110. Itoh M, Ide S, Takashima S, et al.  Methyl CpG-binding protein 2 (a mutation of which causes Rett Syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains.  J Neuropathol Exp Neurol 2007;66:117-123
  111. Iuchi S, Hoffner G, Verbeke P, Djian P and Green H. Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine. Proc. Natl. Acad. Sci. USA. 2003, 100:2409-2414.
  112. Jang J, Jo D-G, Chung C-W, Jung Y-K.  Novel genes, ADRG2 and ADRG4, isolated by cell-based functional screening increases Ab generation by enhancing g-secretase activity. Neuroscience 2006
  113. Jiang, Y-H., Sahoo, T., Michaelis, R.C.,  Bercovich, D., Bressler, J., Kashork, C.D.,  Liu, Q., Shaffer, L.G., Schroer,R.J.,  Stockton, D.W., Spielman, R.S., Stevenson, R.E. &  Beaudet; A.L.  2004.  A mixed epigenetic/genetic model for oligogenic inheritance of autism with a limited role for UBE3A.  Am J Med Genet A. Nov 15;131(1):1-10.
  114. Junaid MA & Pullarkat RK (2001). Proteomic approach for the elucidation of biological defects in autism.  Journal of Autism and Developmental Disorders 31: 557-560.
  115. Junaid, M.A., Kowal, D., Barua, M., Pullarkat, P.S., Skower-Brooks, S., and Pullarkat, R.K.(2004) Proteomic studies identified a single nucleotide polymorphism in glyoxalase I as autism susceptibility factor. Am J Med Genet 2004 Sep 22;[epub ahead of print].
  116. Konradi, C., Walsh, J., Benes, F., Heckers, S.   Down-regulation of electron transport enzymes in hippocampus of bipolar disorder. Archives of General Psychiatry 2004: 61:300-308.
  117. Koul, O.  Myelin in Autism, Chapter in The Neurobiology of Autism, ed. Bauman ML and Kemper T, Johns Hopkins Univ. Press, Baltimore, MD, 2006.
  118. Kumar, P., Ambasta, R., Veeresh, V., Rosen, K., Kosik, K., Band, H., Mestril, R., Patterson, C., Querfurth, H. CHIP and HSPs interact with bAPP in a proteasome-dependent manner and influsence Ab metabolism. Hum. Mol. Genetics. 16:7, 848-864, 2007.
  119. Lahousse SA, Stopa EG, Mulberg AE, de la Monte SM.  Reduced expression of the cystic fibrosis transmembrane conductance regulator gene in the hypothalamus of patients with Alzheimer’s disease.  J Alzheimers Dis. Dec;5(6):455-62, 2003.
  120. Lipinski B, Sajdel-Sulkowska EM.  New insight into Alzheimer disease: demonstration of fibrin(ogen)-serum albumin insoluble deposits in brain tissue.  Alzheimer Disease and Associated Disorders.  20:323-326, 2006.
  121. LaSalle JM, Goldstine J, Balmer D, and Greco CM.  2001.  Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression in normal and Rett syndrome brain by laser scanning cytometry. Hum. Mol. Genet. 10:1729-1740.
  122. Laurence JE, Fatemi SH.  Glial fibrillary acidic protein is elevated in superior frontal, parietal and cerebellar cortices of autistic subjects.  Cerebellum 4:206-210, 2005.
  123. Lee DA, Lopez-Alberola R, Bhattacharjee M.  Childhood autism: a circuit syndrome? Neurologist. 2003 Mar;9(2):99-109.
  124. LuGuang Luo, QuanFu Mao, IMD Jackson, EG Stopa.  Thyrotropin Releasing Hormone (TRH) in the Alzheimer Hippocampus.  J Alzheimers Dis. 2002 Apr;4(2):97-103.  PMID:  12417381 
  125. MacDonald AB.  Alzheimer’s disease Braak Stage progressions:  Reexamined and redefined as Borrelia infection transmission through circuits.  Med Hypotheses (2006), doi:10.1016/j.mehy.  2006.09.054.
  126. MacDonald AB.  Alzheimer’s neuroborreliosis with trans-synpatic spread of infection and neurofibrillary tangles derived from intraneuronal spirochetes.  Med Hypotheses (2006), doi:10.1016/j.mehy.2006.08.043.
  127. MacDonald AB.  Spirochetal cyst forms in neurodegenerative disorders, hiding in plain sight.  Med Hypotheses (2006) doi:10.1016/j.mehy.2006.04.025.
  128. MacDonald AB.  Transfection “Junk” DNA – A link to the pathogenesis of Alzheimer’s disease?  Med Hypotheses (2005) doi:10.1016/j.mehy.2005.12.028.
  129. MacDonald AB.  A life cycle for Borrelia Spirochetes?  Med Hypotheses (2005) doi:10.1016/j.mehy.2006.03.028.
  130. MacDonald AB.  Plaques of Alzheimer’s disease originate from cycts of Borrelia burgdorferi, the Lyme disease spirochete. Med Hypotheses (2005) doi:10.1016/j.mehy.2006.03.028.
  131. Marks N, Berg MJ.  Glucosyl ceramide synthase in Alzheimer’s brain correlates with abonormal increase in long chain ceramides (inCer), 32nd FEBS Congress, submitted. 2007
  132. Martchek M, Thevarkunnel S, Bauman M, Blatt G, Kemper T. (2006) Lack of evidence of neuropathology in the locus coeruleus in autism. Acta Neuropathol (Berl). 111:497-9.
  133. Martin-Ruiz CM, Lee M, Perry RH, Baumann M, Court JA, Perry EK. 2004. Molecular analysis of nicotinic receptor expression in autism.  Brain Res Mol Brain Res.  Apr 7;123(1-2):81-90.
  134. McNamara RK, Hahn CG, Jandacek R, Rider T, Tso P, Stanford KE, and Richand NM.  Selective Deficits in the Omega-3 Fatty Acid Docosahexaeonic Acid in the Postmortem Orbitofrontal Cortex of Patients with Major Depressive Disorder.  Biological Psychiatry, 62(1):17-24, 2007.
  135. McNamara RK, Jandecek R, Rider T, Tso P, Stanford KE, Hahn CG,  Richtand NM,  Stanford K.  Abnormalities in the Fatty Acid Composition of the Postmortem Orbitofrontal Cortex of Schizophrenia Patients:  Gender Differences and Partial Normalization with Antipsychotic Medications.  Schizophrenia Research, 91(1-3):37-50, 2007.
  136. McNamara RK, Jandecek R, Rider T, Tso P, Stanford KE, Hahn CG, and Richtand NM.    Deficits in Docosahexaenoic Acid and Associated Elevations n the Metabolism of Arachidonic Acid and Saturated Fatty Acids in the Postmortem Orbitofrontal Cortex of Patients with Bipolar Disorder. Psychiatry Research, under revision.
  137. Minzer K, Lee O, Hong JJ, Singer HS. Increased prefrontal D2 protein in Tourette syndrome: a postmortem analysis of frontal cortex and striatum.  J Neurological Sci 219;55-61, 2004
  138. Mukaetova-Ladinska EB, Arnold H, Jaros E, Perry R, Perry E. 2004. Depletion of MAP2 expression and laminar cytoarchitectonic changes in dorsolateral prefrontal cortex in adult autistic individuals. Neuropathol Appl Neurobiol. 2004 Dec;30(6):615-23.
  139. Nagarajan RP, Hogart A, Gwye Y, Martin M, and LaSalle JM. 2006. Reduced MeCP2 expression is frequent in autism frontal cortex and correlates with aberrant MECP2 promoter methylation Epigenetics, 4:172-182.
  140. Nguyen T, Galvan V, Zhang J, Bredesen DE.  2007.  p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664.  J Neurochem.  In press.
  141. Nixon RA, Mathews PM, Cataldo AM.  The neuronal endosomal-lysosomal system in Alzheimer’s disease.  Journal of Alzheimer’s Disease 2001; 3:97-107.
  142. Nixon RA, Mathews PM, Cataldo AM, Mohan PS, Schmidt SD, Duff K, Berg M, Marks N, Peterhoff C, Sershen H. (2001).  In Vivo Perturbation of Lysosomal Function Promotes Neurodegeneration in the PS1M146V/APPk670N. M671L Mouse Model of Alzheimer’s Disease Pathology.  In: Alzheimer’s Disease: Advances in Etiology, Pathogenesis and Therapeutics. (K. Iqbal, SS Sisodia and B. Winblad, eds.).  John Wiley and Sons Ltd., New York, 461-467.
  143. Palmen SJ, van Engeland H, Hof PR, Schmitz C. 2004.  Neuropathological findings in autism.  Brain. 2004 Dec;127(Pt 12):2572-83. Epub 2004 Aug 25.
  144. Pandy G, Ren X, Rizavi H, Teppen T, Dwivedi Y.  Protein kinase C in postmortem brain of bipolar and schizophrenia subjects (under preparation).  2007
  145. Pantazopoulos, X., Stone, D., Walsh, J.P., Benes, F.M.  Differences in the cellular distribution of D1 receptor mRNA in the hippocampus of bipolars and schizophrenics. Synapse, 2004; 54: 147-155.
  146. Pantazopoulos H, Lange N, Baldessarini RJ, Berretta S. Parvalbumin neurons in the entorhinal cortex of subjects diagnosed with bipolar disorder or schizophrenia. Biol Psychiatry 61:640-652 (2007).
  147. Pardo, CA, Vargas, DL & AW Zimmerman. 2005.  Immunity, neuroglia and neuroinflammation in autism.  International Review of Psychiatry, December 2005; 17(6): 485–495.
  148. Peddada S, Yasui DH, and LaSalle, JM.  2006.  Inhibitors of differentiation (ID1, ID2, ID3, ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndrome. Hum. Mol. Genet. 15:2003-2014.
  149. Peel AL,  Sorscher N, Kim J, Galvan V, Chen S and Bredesen DE.  Tau phosphorylation in Alzheimer’s disease.  NeuroMol Med 2004; 5 205-218.
  150. Perkins DO, Jeffries C, Jarskog LF, Thompson JM, Newman M, Parker JS, Jin J, Hammond SM.  MiRNA expression profiling in the prefrontal cortex of individuals with schizophrenia.  Genome Biology. 2007;8(2):R27.  Full online access (doi;10.1186/gb-2007-9-2-r27). In press.
  151. Perry EK, Lee ML, Martin-Ruiz CM, Court JA, Volsen SG, Merrit J, Folly E, Iversen PE, Bauman ML, Perry RH, Wenk GL. 2001. Cholinergic activity in autism: abnormalities in the cerebral cortex and basal forebrain. Am J Psychiatry. 2001 Jul;158(7):1058-66.
  152. Pickett, J. (2003) Autism Tissue Program: The Gift of Hope.  Exceptional Parent Magazine. Vol. 33 (6): 106-109.
  153. Pickett J. & London E. 2005.  The Neuropathology of Autism: A Review.  Journal of Neuropathology and Experimental Neurology.  64(11):1-11.
  154. Pickett et.al.  2006.  1998-2002 update on causes of death in autism [letter].  Journal of Autism and Developmental Disorders. [E-publication ahead of print]
  155. Purcell, A.K., Jeon, O. & Pevsner, J. (2001). The Abnormal Regulation of Gene Expression in Autistic Brain. Journal of Autism and Developmental Disorders. 31: 545-550.
  156. Ray MA, Graham AJ, Lee M, Perry RH, Court JA, Perry EK. 2005. Neuronal nicotinic acetylcholine receptor subunits in autism: an immunohistochemical investigation in the thalamus. Neurobiol Dis. Aug;19(3):366-77.
  157. Redcay E & Courchesne E.  When is the brain enlarged in autism? A meta-analysis of all brain size Reports. Biol Psychiatry. 2005 Jul 1;58(1):1-9.
  158. Rioux, L., Reichenberger, E.R., Fan, Y.L., Bertrand, L. and J. Nissanov (2007) Postmortem estimation of olfactory bulb volume in schizophrenia, in preparation
  159. Rioux, L., Chiappelli, J. and Brisbone, G (2007) Neuregulin 1 and ErbB receptors in the human olfactory bulb, in preparation
  160. Salloway S, Gur T, Berzin T, Tavares R, Zipser B, Correia S, Hovanesian V, Fallon J, Kuo-Leblanc V, Glass D, Hulette C, Rosenberg C, Vitek M, Stopa E.  Effect of APOE genotype on microvascular basement membrane in Alzheimer’s disease.  J Neurosci 2002 Nov 15;203-204:183-7. 
  161. Samaco RC, Nagarajan RP, Braunschweig D, and LaSalle JM.  2004.  Multiple pathways regulate MeCP2 expression in normal human brain development and exhibit defects in autism-spectrum disorders.  Hum. Mol. Genet.  13:629-639.
  162. Samaco RC, Hogart A, and LaSalle JM.  2005. Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3. Hum. Mol. Genet.  14:483-492.
  163. Schumann CM and Amaral DG.  The Human Amygdala in Autism ;  in The Human Amygdala.  Ed. PJ Whales (in press). 
  164. Schumann, C.M., Buonocore, M.H. & Amaral, D.G. (2001).  MRI of the Post-Mortem Autistic Brain  Journal of Autism and Developmental Disorders 31: 561-569.
  165. Schumann CM and Amaral DG.  Stereological evidence for fewer neurons in the Autistic Amygdala.  J Neurosci, 2006,19 ;26(29) :7674-9.
  166. Schumann CM and Amaral DG.  The Social Brain, Amygdala and Autism in Understanding Autism : From basic Neurtoscience to Treatment. Ed. SO Moldin and JLR Rubenstein.  Taylor & Francis Group, Boca Raton, FL, 2006 CRC Press.
  167. Schumann CM and Amaral DG.  Steriological estimation of the number of neurons in the human amygdaloid complex.  Journal of Comparative Neurology, 2005 ;491(4) :320-9.
  168. Shahbazian MD, Antalffy B, Armstrong DL, Zoghbi H.  Insight into Rett syndrome :MeCP2 levels display tissue and cell-specific differences and correlate with neuronal maturation.  Human Molecular Genetics 2002,11,115-124.
  169. Shavelle, R., Strauss, R. and Pickett, J.  (2001). Causes of Death in Autism.  Journal of Autism and Developmental Disorders 31: 569-576
  170. Song S, Kim S-Y, Hong Y-M, Jo D-G, Lee J-Y, Shim SM, Chung C-W, Seo SJ, Yoo YJ, Koh J-Y, Lee MC, Yates AJ, Ichijo H, and Jung Y-K.  Essential Role of E2-25K/Hip-2 in Mediating Amyloid-_ Neurotoxicity.  Molecular Cell, 12;553-563, 2003
  171. Stopa, EG, Kim, S, Song, P, Berzin, T, Kuo-Leblanc, V, Rodriguez-Wolf, M, Baird, A, and Johanson, CE.  Human choroid plexus growth factors:  What are the implications for CSF and brain? Exp Neurol. 2001 Jan;167(1):40-7.
  172. Thatcher KN, Peddada S, Yasui DH, and LaSalle JM. 2005.  Homologous pairing of 15q11-13 imprinted domains in brain is developmentally regulated but deficient in Rett and autism samples. Hum. Mol. Genet. 14:785-797.
  173. Thatcher KN and LaSalle JM. 2006.  Dynamic changes in Histone H3 lysine 9 acetylation localization patterns during neuronal maturation require MeCP2.  Epigenetics. 1:24-31.
  174. Todtenkopf, M.S., Vincent, S.L and Benes, F.M.  A cross-study meta-analysis and 3-dimensional validation of cell counting in cingulate cortex of schizophrenic and bipolar brain.  Schizophrenia Research 2005; 73:79-89.
  175. Vargas D.L., Nascimbene, C. Krishnan, C. Zimmerman, A.W. and Pardo, C.A.  2005.  Increased neuroglial activation and neuroinflammation in the brain of patients with autism.  Annals of Neurology 57(1):67-81.
  176. Veldic M, Caruncho HJ, Liu WS, Davis J, Satta r, Grayson DR, Guidotti A, Costa E.  DNA methyltransferase-1 (DNMT1) overexpression in telencephalic GABAergic interneurons of schizophrenia brains.  PROCEEDINGS OF NATIONAL ACADEMY OF SCIENCES 101:348-353, 2004
  177. Veldic M, Guidotti A, Maloku E, Davis J, Costa E.  In psychosiscortical interneurons overexpress DNA-methyltransferase1.  PROCEEDINGS OF NATIONAL ACADEMY OF SCIENCES 102;2152-2157, 2005
  178. Veldie M, Kadriu B, Maloku E, Agis-Balboa RC, Guidotti A, Davis JM, Costa E.  Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. Schizophrenia Research 91:51-61, 2007
  179. Woo, W., Walsh, J., Benes, F.M.  Decreased expression of the NR2A subunit in GABAergic neurons in anterior cingulate cortex of schizophrenics and bipolars.  Archives of General Psychiatry 2004: 61: 649-657.
  180. Woo W, Kim A, Viscidi E.  Disease-specific alterations in glutamatergic neurotransmission on inhibitory interneurons in the prefrontal cortex in schizophrenia.  Submitted
  181. Woo W,  Shrestha K, Amstrong C,  Minns M,  Walsh JP, Benes FM.  Differential alterations of kainate receptor subunits in GABAergic interneurons in the anterior cingulate cortex in schizophrenia and bipolar disorder.  Schizophrenia Research 2007; in press.
  182. Wu J, Chang Y, Li G, Xue F, Dechon J, Ellsworth K, Liu Q, Yang K, Bahafroani N, Zheng C, Zhang J, Rekate H, Rho JM, Kerrigan JF.  Electrophysiological Properties and Subunit Composition of GABAA Receptors in Patients with Gelastic Seizures and Hypothalamic Hamartoma.  J Neurophysiol 2007 (In print)
  183. Yoon DY, Gause CD, Leckman JF, Singer HS.  Frontal dopaminergic abnormality in Tourette syndrome: A postmortem analysis.  Neurosci 15;255-:50-6, 2007
  184. Zipser BD, Johanson CE, Gonzalez L, Berzin TM, Tavares R, Hulette CM, Vitek MP, Hovanesian V, Stopa EG. Microvascular injury and blood-brain barrier leakage in Alzheimer's disease. Neurobiol Aging. 2006 Jun 15.
  185. Zuccato C., Belyaev N., Conforti P., Ooi L., Tartari M., Papadimou E., MacDonald M.E.,Fossale E., Zeitlin S., Buckley N.J. and Cattaneo E.  Widespread disruption of REST/NRSF occupancy of its target genes in Huntington’s Disease. J.  Neurosci, June 27, 2007, 27(26):6972- 6983.
  186. Abu-Elneel, K., Liu, T., Gazzaniga, F. S., Nishimura, Y., Wall, D. P., Geschwind, D. H., Lao, K. & Kosik, K. S. 2008. Heterogeneous dysregulation of microRNAs across the autism spectrum. Neurogenetics, 9, 153-161.
  187. Abuhatzira, L., Shemer, R. & Razin, A. 2009. MeCP2 involvement in the regulation of neuronal alpha-tubulin production. Hum Mol Genet, 18, 1415-1423.
  188. André, W., Sandt, C., Dumas, P., Djian, P. & Hoffner, G. 2012. Structure of inclusions of Huntington disease brain revealed by synchrotron infrared microspectroscopy: polymorphism and relevance to cytotoxicity. Chem Biol, Submitted.
  189. Avino, T. A. & Hutsler, J. J. 2010. Abnormal cell patterning at the cortical gray-white matter boundary in autism spectrum disorders. Brain Res, 1360, 138-146.
  190. Azmitia, E. C. & Nixon, R. 2008. Dystrophic serotonergic axons in neurodegenerative diseases.  Brain Res,1217, 185-19.
  191. Azmitia, E. C., Singh, J. S., Hou, X. P. & Wegiel, J. 2011a. Dystrophic serotonin axons in postmortem brains from young autism patients.  Anat Rec (Hoboken), 294, 1653-1662.
  192. Azmitia, E. C., Singh, J. S. & Whitaker-Azmitia, P. M. 2011b. Increased serotonin axons (immunoreactive to 5-HT transporter) in postmortem brains from young autism donors. Neuropharmacology, 60, 1347-1354.
  193. Ballester, L. Y., Capo-Velez, C. M., Garcia-Beltran, W. F., Ramos, F. M., Vazquez-Rosa, E., Rios, R., Mercado, J. R., Melendez, R. I. & Lasalde-Dominicci, J. A. 2012. Up-regulation of the neuronal nicotinic receptor alpha7 by HIV glycoprotein 120: potential implications for HIV-associated neurocognitive disorder.  J Biol Chem, 287, 3079-3086.
  194. Banigan, M. G., Kao, P. F., Kozubek, J. A., Winslow, A. R., Medina, J., Costa, J., Schmitt, A., Cabral, H., Vanderburg, C. R. & Delalle, I. 2013. Differential expression of exosomal miRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients.  PLoS One, In press.
  195. Beasley, C. L., Pennington, K., Behan, A., Wait, R., Dunn, M. J. & Cotter, D. 2006. Proteomic analysis of the anterior cingulate cortex in the major psychiatric disorders: Evidence for disease-associated changes.  Proteomics, 6, 3414-3425.
  196. Behan, A. T., Byrne, C., Dunn, M. J., Cagney, G. & Cotter, D. R. 2009. Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression.  Mol Psychiatry, 14, 601-613.
  197. Benes, F. M. 2010a. Amygdalocortical circuitry in schizophrenia: from circuits to molecules. Neuropsychopharmacology, 35, 239-257.
  198. Benes, F. M. 2010b. Relationship of GAD(67) regulation to cell cycle and DNA repair in GABA neurons in the adult hippocampus: bipolar disorder versus schizophrenia. Cell Cycle, 9, 625-627.
  199. Benes, F. M. 2010c. Searching for unique endophenotypes for schizophrenia and bipolar disorder within neural circuits and their unique molecular regulatory mechanisms. In: TAMMINGA, C., SEROVATKA, P. J. & REVIER, D. A. (eds.) Deconstructing Psychosis: Refining the Research Agenda for DSMV,99-107; American Psychiatric Institute for Research and Teaching, WHO and NIH. 
  200. Benes, F. M. 2011a. Neurobiology of bipolar disorder:  From circuits to cells to molecular regulation. In: MANJI, H. K. & ZARATE, C. (eds.) Current Topics in Behavioral Neuroscience 5:127-138.
  201. Benes, F. M. 2011b. Regulation of cell cycle and DNA repair in post-mitotic GABA neurons in psychotic disorders. Neuropharmacology, 60, 1232-1242.
  202. Benes, F. M. 2012a. GABAergic circuits in schizophrenia: targets for novel antipsychotics?  . In: HOFMANN, F. B. (ed.) Handbook of Experimental Pharmacology213Berlin: Springer. 401-419.
  203. Benes, F. M. 2012b. A new paradigm for understanding gamma-aminobutyric acid cell pathology in schizophrenia? Biol Psychiatry, 72, 712-713.
  204. Benes, F. M., Cunningham, M. G., Berretta, S. & Gisabella, B. 2009a. Course and pattern of cingulated pathology in schizophrenia. In: VOGT, B. A. (ed.) Cingulate Neurobiology and Disease. Second Edition.  Oxford University Press. 655-678.
  205. Benes, F. M., Lim, B., Matzilevich, D., Subburaju, S. & Walsh, J. P. 2008a. Circuitry-based gene expression profiles in GABA cells of the trisynaptic pathway in schizophrenics versus bipolars. Proc Natl Acad Sci U S A, 105, 20935-20940.
  206. Benes, F. M., Lim, B., Matzilevich, D. & Walsh, J. 2008b. Identifying Novel Target Genes in Psychotic Disorder Network Association Analyses. In: O'DONNELL, P. (ed.) Cortical Deficits in Schizophrenia.  From Genes to Function. New York: Springer. 191-204.
  207. Benes, F. M., Lim, B. & Subburaju, S. 2009b. Site-specific regulation of cell cycle and DNA repair in post-mitotic GABA cells in schizophrenic versus bipolars.  Proc Natl Acad Sci U S A, 106, 11731-11736.
  208. Berman, A. E., Chan, W. Y., Brennan, A. M., Reyes, R. C., Adler, B. L., Suh, S. W., Kauppinen, T. M., Edling, Y. & Swanson, R. A. 2011. N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse.  Ann Neurol, 69, 509-520.
  209. Berretta, S. 2012. Extracellular matrix abnormalities in schizophrenia.  Neuropharmacology, 62, 1584-1597.
  210. Berretta, S., Gisabella, B. & Benes, F. M. 2009. A rodent model of schizophrenia derived from postmortem studies.  Behav Brain Res, 204, 363-368.
  211. Bitanihirwe, B. K., Lim, M. P., Kelley, J. F., Kaneko, T. & Woo, T. U. W. 2009. Glutamatergic deficits and parvalbumin-containing inhibitory neurons in the prefrontal cortex in schizophrenia. BMC Psychiatry, 9, 71.
  212. Blatt, G. J. & Fatemi, S. H. 2011. Alterations in GABAergic biomarkers in the autism brain: research findings and clinical implications.  Anat Rec (Hoboken), 294, 1646-1652.
  213. Bliss, L. A., Sams, M. R., Deep-Soboslay, A., Ren-Patterson, R., Jaffe, A. E., Chenoweth, J. G., Jaishankar, A., Kleinman, J. E. & Hyde, T. M. 2012. Use of postmortem human dura mater and scalp for deriving human fibroblast cultures.  PLoS One, 7, e45282.
  214. Casanova, M. F., El-Baz, A., Mott, M., Mannheim, G., Hassan, H., Fahmi, R., Giedd, J., Rumsey, J. M., Switala, A. E. & Farag, A. 2009. Reduced gyral window and corpus callosum size in autism: possible macroscopic correlates of a minicolumnopathy. J Autism Dev Disord, 39, 751-764.
  215. Casanova, M. F., El-Baz, A., Vanbogaert, E., Narahari, P. & Switala, A. 2010a. A topographic study of minicolumnar core width by lamina comparison between autistic subjects and controls: possible minicolumnar disruption due to an anatomical element in-common to multiple laminae. Brain Pathol, 20, 451-458.
  216. Casanova, M. F., El-Baz, A. S., Giedd, J., Rumsey, J. M. & Switala, A. E. 2010b. Increased white matter gyral depth in dyslexia: implications for corticocortical connectivity. J Autism Dev Disord, 40, 21-29.
  217. Cataldo, A. M., Mathews, P. M., Boiteau, A. B., Hassinger, L. C., Peterhoff, C. M., Jiang, Y., Mullaney, K., Neve, R. L., Gruenberg, J. & Nixon, R. A. 2008. Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects. Am J Pathol, 173, 370-384.
  218. Catoire, H., Dion, P. A., Xiong, L., Amari, M., Gaudet, R., Girard, S. L., Noreau, A., Gaspar, C., Turecki, G., Montplaisir, J. Y., Parker, J. A. & Rouleau, G. A. 2011. Restless legs syndrome-associated MEIS1 risk variant influences iron homeostasis. Ann Neurol, 70, 170-175.
  219. Chauhan, A., Audhya, T. & Chauhan, V. 2012. Brain region-specific glutathione redox imbalance in autism. Neurochem Res, 37, 1681-1689.
  220. Chauhan, A., Gu, F., Essa, M. M., Wegiel, J., Kaur, K., Brown, W. T. & Chauhan, V. 2011. Brain region-specific deficit in mitochondrial electron transport chain complexes in children with autism. J Neurochem, 117, 209-220.
  221. Chen, K.H., Reese, E.A., Kim, H.W., Rapoport S.I. & Rao, J.S. 2011.  Disturbed neurotransmitter expression in Alzheimer’s disease brain. J Alzheimers Dis, 26(4):755-66.
  222. Chow, M. L., Li, H. R., Winn, M. E., April, C., Barnes, C. C., Wynshaw-Boris, A., Fan, J. B., Fu, X. D., Courchesne, E. & Schork, N. J. 2011. Genome-wide expression assay comparison across frozen and fixed postmortem brain tissue samples. BMC Genomics, 12, 449.
  223. Chow, M. L., Pramparo, T., Winn, M. E., Barnes, C. C., Li, H. R., Weiss, L., Fan, J. B., Murray, S., April, C., Belinson, H., Fu, X. D., Wynshaw-Boris, A., Schork, N. J. & Courchesne, E. 2012. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet, 8, e1002592.
  224. Cohen, O. S., Mccoy, S. Y., Middleton, F. A., Bialosuknia, S., Zhang-James, Y., Liu, L., Tsuang, M. T., Faraone, S. V. & Glatt, S. J. 2012. Transcriptomic analysis of postmortem brain identifies dysregulated splicing events in novel candidate genes for schizophrenia. Schizophr Res, 142, 188-199.
  225. Cortes-Canteli, M., Paul, J., Norris, E. H., Bronstein, R., Ahn, H. J., Zamolodchikov, D., Bhuvanendran, S., Fenz, K. M. & Strickland, S. 2010. Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease. Neuron, 66, 695-709.
  226. Cortes-Canteli, M., Zamolodchikov, D., Ahn, H. J., Strickland, S. & Norris, E. H. 2012. Fibrinogen and altered hemostasis in Alzheimer's disease. J Alzheimers Dis, 32, 599-608.
  227. Courchesne, E., Mouton, P. R., Calhoun, M. E., Semendeferi, K., Ahrens-Barbeau, C., Hallet, M. J., Barnes, C. C. & Pierce, K. 2011. Neuron number and size in prefrontal cortex of children with autism. JAMA, 306, 2001-2010.
  228. Cunningham, M. G., Ames, H. M., Donalds, R. A. & Benes, F. M. 2008a. Construction and implantation of a microinfusion system for sustained delivery of neuroactive agents. J Neurosci Methods, 167, 213-220.
  229. Cunningham, M. G., Bhattacharyya, S. & Benes, F. M. 2008b. Increasing Interaction of amygdalar afferents with GABAergic interneurons between birth and adulthood. Cereb Cortex, 18, 1529-1535.
  230. Davis, J. D., Podolanczuk, A., Donahue, J. E., Stopa, E., Hennessey, J. V., Luo, L. G., Lim, Y. P. & Stern, R. A. 2008. Thyroid hormone levels in the prefrontal cortex of post-mortem brains of Alzheimer's disease patients. Curr Aging Sci, 1, 175-181.
  231. Deep-Soboslay, A., Benes, F. M., Haroutunian, V., Ellis, J. K., Kleinman, J. E. & Hyde, T. M. 2011. Psychiatric brain banking: three perspectives on current trends and future directions. Biol Psychiatry, 69, 104-112.
  232. Dumitriu, A., Latourelle, J. C., Hadzi, T. C., Pankratz, N., Garza, D., Miller, J. P., Vance, J. M., Foroud, T., Beach, T. G. & Myers, R. H. 2012a. Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation. PLoS Genet, 8, e1002794.
  233. Dumitriu, A., Moser, C., Hadzi, T. C., Williamson, S. L., Pacheco, C. D., Hendricks, A. E., Latourelle, J. C., Wilk, J. B., Destefano, A. L. & Myers, R. H. 2012b. Postmortem Interval Influences alpha-Synuclein Expression in Parkinson Disease Brain. Parkinsons Dis, 2012, 614212.
  234. Dumitriu, A., Pacheco, C. D., Wilk, J. B., Strathearn, K. E., Latourelle, J. C., Goldwurm, S., Pezzoli, G., Rochet, J. C., Lindquist, S. & Myers, R. H. 2011. Cyclin-G-associated kinase modifies alpha-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study. Hum Mol Genet, 20, 1478-1487.
  235. Earls, L. R., Fricke, R. G., Yu, J., Berry, R. B., Baldwin, L. T. & Zakharenko, S. S. 2012. Age-dependent microRNA control of synaptic plasticity in 22q11 deletion syndrome and schizophrenia. J Neurosci, 32, 14132-14144.
  236. English, J. A., Dicker, P., Focking, M., Dunn, M. J. & Cotter, D. R. 2009. 2-D DIGE analysis implicates cytoskeletal abnormalities in psychiatric disease. Proteomics, 9, 3368-3382.
  237. Evans, T. A., Siedlak, S. L., Lu, L., Fu, X., Wang, Z., Mcginnis, W. R., Fakhoury, E., Castellan, R. J., Hazen, S. L., Walsh, W. J., Lewis, A. T., Salomon, R. G., Smith, M. A., Perry, G. & Zhu, X. 2008. The Autistic Phenotype Exhibits a Remarkably Localized Modification of Brain Protein by Products of Free Radical-Induced Lipid Oxidation. Am J Biochem Biotech, 2, 61-72.
  238. Fabbro, S., Schaller, K. & Seeds, N. W. 2011. Amyloid-beta levels are significantly reduced and spatial memory defects are rescued in a novel neuroserpin-deficient Alzheimer's disease transgenic mouse model. J Neurochem, 118, 928-938.
  239. Fabbro, S. & Seeds, N. W. 2009. Plasminogen activator activity is inhibited while neuroserpin is up-regulated in the Alzheimer disease brain. J Neurochem, 109, 303-315.
  240. Fatemi, S. H. 2008. The hyperglutamatergic hypothesis of autism. Prog Neuropsychopharmacol Biol Psychiatry, 32, 911, author reply 912-913.
  241. Fatemi, S. H., Aldinger, K. A., Ashwood, P., Bauman, M. L., Blaha, C. D., Blatt, G. J., Chauhan, A., Chauhan, V., Dager, S. R., Dickson, P. E., Estes, A. M., Goldowitz, D., Heck, D. H., Kemper, T. L., King, B. H., Martin, L. A., Millen, K. J., Mittleman, G., Mosconi, M. W., Persico, A. M., Sweeney, J. A., Webb, S. J. & Welsh, J. P. 2012. Consensus paper: pathological role of the cerebellum in autism. Cerebellum, 11, 777-807.
  242. Fatemi, S. H. & Folsom, T. D. 2010. FMRP is reduced in cerebella of subjects with autism.  Iranian J Psychiatric Behav Neurosci, 4, 56-57.
  243. Fatemi, S. H. & Folsom, T. D. 2011a. Dysregulation of fragile x mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study. Mol Autism, 2, 6.
  244. Fatemi, S. H. & Folsom, T. D. 2011b. The role of fragile X mental retardation protein in major mental disorders. Neuropharmacology, 60, 1221-1226.
  245. Fatemi, S. H., Folsom, T. D., Kneeland, R. E. & Liesch, S. B. 2011. Metabotropic glutamate receptor 5 upregulation in children with autism is associated with underexpression of both Fragile X mental retardation protein and GABAA receptor beta 3 in adults with autism. Anat Rec (Hoboken), 294, 1635-1645.
  246. Fatemi, S. H., Folsom, T. D., Reutiman, T. J. & Lee, S. 2008. Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism. Synapse, 62, 501-507.
  247. Fatemi, S. H., Folsom, T. D., Reutiman, T. J. & Thuras, P. D. 2009a. Expression of GABA(B) receptors is altered in brains of subjects with autism. Cerebellum, 8, 64-69.
  248. Fatemi, S. H., Reutiman, T. J., Folsom, T. D., Rooney, R. J., Patel, D. H. & Thuras, P. D. 2010. mRNA and protein levels for GABAAalpha4, alpha5, beta1 and GABABR1 receptors are altered in brains from subjects with autism. J Autism Dev Disord, 40, 743-750.
  249. Fatemi, S. H., Reutiman, T. J., Folsom, T. D. & Thuras, P. D. 2009b. GABA(A) receptor downregulation in brains of subjects with autism. J Autism Dev Disord, 39, 223-230.
  250. Folsom, T. D. & Fatemi, S. H. 2012. The involvement of Reelin in neurodevelopmental disorders. NeuropharmacologyIn press.
  251. Furuya, T., Kim, M., Lipinski, M., Li, J., Kim, D., Lu, T., Shen, Y., Rameh, L., Yankner, B., Tsai, L. H. & Yuan, J. 2010. Negative regulation of Vps34 by Cdk mediated phosphorylation. Mol Cell, 38, 500-511.
  252. Garbett K.A., Ebert P.J., Mitchell A., Lintas C., Manzi B., Mirnics K. & Persico A.M.  2008.  Immune transcriptome alterations in the temporal cortex of subjects with autism.  2008.  Neurobiol Dis, 30:303-311
  253. Gavin, D. P., Sharma, R. P., Chase, K. A., Matrisciano, F., Dong, E. & Guidotti, A. 2012. Growth arrest and DNA-damage-inducible, beta (GADD45b)-mediated DNA demethylation in major psychosis. Neuropsychopharmacology, 37, 531-542.
  254. Ginsberg, M. R., Rubin, R. A., Falcone, T., Ting, A. H. & Natowicz, M. R. 2012. Brain transcriptional and epigenetic associations with autism. PLoS One, 7, e44736.
  255. Gkogkas, C. G., Khoutorsky, A., Ran, I., Rampakakis, E., Nevarko, T., Weatherill, D. B., Vasuta, C., Yee, S., Truitt, M., Dallaire, P., Major, F., Lasko, P., Ruggero, D., Nader, K., Lacaille, J. C. & Sonenberg, N. 2012. Autism-related deficits via dysregulated eIF4E-dependent translational control.  Nature.
  256. Gonzalez, A. M., Podvin, S., Lin, S. Y., Miller, M. C., Botfield, H., Leadbeater, W. E., Roberton, A., Dang, X., Knowling, S. E., Cardenas-Galindo, E., Donahue, J. E., Stopa, E. G., Johanson, C. E., Coimbra, R., Eliceiri, B. P. & Baird, A. 2011. Ecrg4 expression and its product augurin in the choroid plexus: impact on fetal brain development, cerebrospinal fluid homeostasis and neuroprogenitor cell response to CNS injury. Fluids Barriers CNS, 8, 6.
  257. Gonzalez, A. M., Taylor, W. M., Johanson, C. E., King, J. C., Leadbeater, W. E., Stopa, E. G. & Baird, A. 2010. Co-localization and regulation of basic fibroblast growth factor and arginine vasopressin in neuroendocrine cells of the rat and human brain. Cerebrospinal Fluid Res, 7, 13.
  258. Gregg, J. P., Lit, L., Baron, C. A., Hertz-Picciotto, I., Walker, W., Davis, R. A., Croen, L. A., Ozonoff, S., Hansen, R., Pessah, I. N. & Sharp, F. R. 2008. Gene expression changes in children with autism. Genomics, 91, 22-29.
  259. Gregory, S. G., Connelly, J. J., Towers, A. J., Johnson, J., Biscocho, D., Markunas, C. A., Lintas, C., Abramson, R. K., Wright, H. H., Ellis, P., Langford, C. F., Worley, G., Delong, G. R., Murphy, S. K., Cuccaro, M. L., Persico, A. & Pericak-Vance, M. A. 2009. Genomic and epigenetic evidence for oxytocin receptor deficiency in autism. BMC Med, 7, 62.
  260. Guidotti, A., Dong, E., Gavin, D. P., Veldic, M., Zhao, W., Bhaumik, D. K., Pandey, S. C. & Grayson, D. R. 2012. DNA Methylation/Demethylation Network Expression in Psychotic Patients with a History of Alcohol Abuse. Alcohol Clin Exp Res.
  261. Hadzi, T. C., Hendricks, A. E., Latourelle, J. C., Lunetta, K. L., Cupples, L. A., Gillis, T., Mysore, J. S., Gusella, J. F., Macdonald, M. E., Myers, R. H. & Vonsattel, J. P. 2012. Assessment of cortical and striatal involvement in 523 Huntington disease brains. Neurology, 79, 1708-1715.
  262. Harper, D. G., Stopa, E. G., Kuo-Leblanc, V., Mckee, A. C., Asayama, K., Volicer, L., Kowall, N. & Satlin, A. 2008. Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia. Brain, 131, 1609-1617.
  263. Hoffner, G., Van Der Rest, G., Dansette, P. M. & Djian, P. 2009. The end product of transglutaminase crosslinking: simultaneous quantitation of [Nepsilon-(gamma-glutamyl) lysine] and lysine by HPLC-MS3. Anal Biochem, 384, 296-304.
  264. Hoffner, G., Hoppilliard, Y., van der Rest, G., Dansette, P. & Ohanessian, G., [Nepsilon-(gamma-glutamyl) lysine] as a potential biomarker in neurological diseases:  new detection method and fragmentation pathways.  J Mass Spectrom, 43:456-469.
  265. Huang, H. S., Cheung, I. & Akbarian, S. 2010. RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder. Autism Res, 3, 153-161
  266. Hutsler, J. J. & Avino, T. A. 2012. Sigmoid fits to locate and characterize cortical boundaries in human cerebral cortex. J Neurosci Methods, 212, 242-246.
  267. Hutsler, J. J. & Zhang, H. 2010. Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders. Brain Res, 1309, 83-94.
  268. Igarashi, M., Ma, K., Gao, F., Kim, H.W., Rapoport, S.I. & Rao, J.S.  2011.  Distrubed choline plasmalogen and phospholipid fatty acid concentrations in Alzheimer’s disease prefrontal cortex.  JAlzheimers Dis, 24(3):507-17.
  269. Igarashi, M., Ma, K., Gao, F., Kim, H.W., Greenstein, D., Rapoport, S.I. & Rao, J.S., 2010.  Brain lipid concentrations in bipolar disorder.  J Psychiatr Res,44(3):177-82.
  270. Ihara, Y., Morishima-Kawashima, M. & Nixon, R. 2012. The ubiquitin-proteasome system and the autophagic-lysosomal system in Alzheimer disease. Cold Spring Harb Perspect Med, 2.
  271. Jacot-Descombes, S., Uppal, N., Wicinski, B., Santos, M., Schmeidler, J., Giannakopoulos, P., Heinsen, H., Schmitz, C. & Hof, P. R. 2012. Decreased pyramidal neuron size in Brodmann areas 44 and 45 in patients with autism. Acta Neuropathol, 124, 67-79.
  272. Ji, L., Chauhan, V., Flory, M. J. & Chauhan, A. 2011. Brain region-specific decrease in the activity and expression of protein kinase A in the frontal cortex of regressive autism. PLoS One, 6, e23751.
  273. Kaminsky, Z., Tochigi, M., Jia, P., Pal, M., Mill, J., Kwan, A., Ioshikhes, I., Vincent, J. B., Kennedy, J. L., Strauss, J., Pai, S., Wang, S. C. & Petronis, A. 2012. A multi-tissue analysis identifies HLA complex group 9 gene methylation differences in bipolar disorder. Mol Psychiatry, 17, 728-740.
  274. Kataoka, Y., Kalanithi, P. S., Grantz, H., Schwartz, M. L., Saper, C., Leckman, J. F. & Vaccarino, F. M. 2010. Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. J Comp Neurol, 518, 277-291.
  275. Kerin, T., Ramanathan, A., Rivas, K., Grepo, N., Coetzee, G. A. & Campbell, D. B. 2012. A noncoding RNA antisense to moesin at 5p14.1 in autism. Sci Transl Med, 4, 128ra140.
  276. Khare, T., Pai, S., Koncevicius, K., Pal, M., Kriukiene, E., Liutkeviciute, Z., Irimia, M., Jia, P., Ptak, C., Xia, M., Tice, R., Tochigi, M., Morera, S., Nazarians, A., Belsham, D., Wong, A. H., Blencowe, B. J., Wang, S. C., Kapranov, P., Kustra, R., Labrie, V., Klimasauskas, S. & Petronis, A. 2012. 5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary. Nat Struct Mol Biol, 19, 1037-1043.
  277. Kim, H.W., Rapoport, S.I. & Rao, J.S.  2011.  Altered arachidonic acid cascade enzymes in postmortem brain from bipolar disorder patients. Mol Psychiatry,16(4):419-28.
  278. Kim, H.W., Rapoport, S.I. & Rao, J.S.  2010.  Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients.  Neurobiol Dis, 37(3):596-603.
  279. Konradi, C., Yang, C. K., Zimmerman, E. I., Lohmann, K. M., Gresch, P., Pantazopoulos, H., Berretta, S. & Heckers, S. 2011a. Hippocampal interneurons are abnormal in schizophrenia. Schizophr Res, 131, 165-173
  280. Konradi, C., Zimmerman, E. I., Yang, C. K., Lohmann, K. M., Gresch, P., Pantazopoulos, H., Berretta, S. & Heckers, S. 2011b. Hippocampal interneurons in bipolar disorder. Arch Gen Psychiatry, 68, 340-350.
  281. Kulesza, R. J., Jr., Lukose, R. & Stevens, L. V. 2011. Malformation of the human superior olive in autistic spectrum disorders. Brain Res, 1367, 360-371.
  282. Kulesza, R. J. & Mangunay, K. 2008. Morphological features of the medial superior olive in autism. Brain Res, 1200, 132-137.
  283. Lanoue, A. C., Dumitriu, A., Myers, R. H. & Soghomonian, J. J. 2010. Decreased glutamic acid decarboxylase mRNA expression in prefrontal cortex in Parkinson's disease. Exp Neurol, 226, 207-217.
  284. Latourelle, J. C., Dumitriu, A., Hadzi, T. C., Beach, T. G. & Myers, R. H. 2012. Evaluation of Parkinson disease risk variants as expression-QTLs. PLoS One, 7, e46199.
  285. Leal, M. C., Surace, E. I., Holgado, M. P., Ferrari, C. C., Tarelli, R., Pitossi, F., Wisniewski, T., Castano, E. M. & Morelli, L. 2012. Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Abeta metabolism. Biochim Biophys Acta, 1823, 227-235.
  286. Lee, J. M., Gillis, T., Mysore, J. S., Ramos, E. M., Myers, R. H., Hayden, M. R., Morrison, P. J., Nance, M., Ross, C. A., Margolis, R. L., Squitieri, F., Griguoli, A., Di Donato, S., Gomez-Tortosa, E., Ayuso, C., Suchowersky, O., Trent, R. J., Mccusker, E., Novelletto, A., Frontali, M., Jones, R., Ashizawa, T., Frank, S., Saint-Hilaire, M. H., Hersch, S. M., Rosas, H. D., Lucente, D., Harrison, M. B., Zanko, A., Abramson, R. K., Marder, K., Sequeiros, J., Macdonald, M. E. & Gusella, J. F. 2012a. Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene region. Am J Hum Genet, 90, 434-444.
  287. Lee, J. M., Ramos, E. M., Lee, J. H., Gillis, T., Mysore, J. S., Hayden, M. R., Warby, S. C., Morrison, P., Nance, M., Ross, C. A., Margolis, R. L., Squitieri, F., Orobello, S., Di Donato, S., Gomez-Tortosa, E., Ayuso, C., Suchowersky, O., Trent, R. J., Mccusker, E., Novelletto, A., Frontali, M., Jones, R., Ashizawa, T., Frank, S., Saint-Hilaire, M. H., Hersch, S. M., Rosas, H. D., Lucente, D., Harrison, M. B., Zanko, A., Abramson, R. K., Marder, K., Sequeiros, J., Paulsen, J. S., Landwehrmeyer, G. B., Myers, R. H., Macdonald, M. E. & Gusella, J. F. 2012b. CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology, 78, 690-695.
  288. Lepagnol-Bestel, A. M., Maussion, G., Boda, B., Cardona, A., Iwayama, Y., Delezoide, A. L., Moalic, J. M., Muller, D., Dean, B., Yoshikawa, T., Gorwood, P., Buxbaum, J. D., Ramoz, N. & Simonneau, M. 2008. SLC25A12 expression is associated with neurite outgrowth and is upregulated in the prefrontal cortex of autistic subjects. Mol Psychiatry, 13, 385-397.
  289. Limon, A., Reyes-Ruiz, J. M. & Miledi, R. 2008. Microtransplantation of neurotransmitter receptors from postmortem autistic brains to Xenopus oocytes. Proc Natl Acad Sci U S A, 105, 10973-10977.
  290. Lintas, C., Guidi, F., Manzi, B., Mancini, A., Curatolo, P. & Persico, A. M. 2011. Lack of infection with XMRV or other MLV-related viruses in blood, post-mortem brains and paternal gametes of autistic individuals. PLoS One, 6, e16609. Lintas, C., Altieri, L., Lombardi, F., Sacco, R. & Persico, A. M. 2010. Association of autism with polyomavirus infection in postmortem brains. J Neurovirol, 16, 141-149.
  291. Lintas, C. and Persico, A.M.  2010.  Neocortical RELN promoter methylation increases significantly after puberty. Neuroreport, 21:114-118
  292. Lintas, C., Sacco, R., Garbett, K., Mirnics, K., Militerni, R., Bravaccio, C., Curatolo, .P, Manzi, B., Schneider, C., Melmed, R., Elia, M., Pascucci, T., Puglisi-Allegra, S., Reichelt, K.L. and Persico, A.M.  2009.  Involvement of the PRKCB1 gene in autistic disorder: significant genetic association and reduced neocortical gene expression.  Mol Psychiatry, 46:1-8 
  293. Lintas, C., Sacco, R., Garbett, K., Mirnics, K., Militerni, R., Bravaccio, C., Curatolo, P., Manzi, B., Schneider, C., Melmed, R., Elia, M., Pascucci, T., Puglisi-Allegra, S., Reichelt, K. L. & Persico, A. M. 2009. Involvement of the PRKCB1 gene in autistic disorder: significant genetic association and reduced neocortical gene expression. Mol Psychiatry, 14, 705-718.
  294. Lisman, J. E., Coyle, J. T., Green, R. W., Javitt, D. C., Benes, F. M., Heckers, S. & Grace, A. A. 2008. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci, 31, 234-242.
  295. Liu, H. C., Enikolopov, G. & Chen, Y. 2012. Cul4B regulates neural progenitor cell growth. BMC Neurosci, 13, 112.
  296. López-Hurtado, E. & Preieto, J. J. 2008. A Microscopic Study of Language-Related Cortex in Autism. Am J Biochem Biotech, 4, 130-145.
  297. Maussion, G., Carayol, J., Lepagnol-Bestel, A. M., Tores, F., Loe-Mie, Y., Milbreta, U., Rousseau, F., Fontaine, K., Renaud, J., Moalic, J. M., Philippi, A., Chedotal, A., Gorwood, P., Ramoz, N., Hager, J. & Simonneau, M. 2008. Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism. Hum Mol Genet, 17, 2541-2551.
  298. Mclean, J. R., Hallett, P. J., Cooper, O., Stanley, M. & Isacson, O. 2012. Transcript expression levels of full-length alpha-synuclein and its three alternatively spliced variants in Parkinson's disease brain regions and in a transgenic mouse model of alpha-synuclein overexpression. Mol Cell Neurosci, 49, 230-239.
  299. Miller, M. C., Lambert-Messerlian, G. M., Eklund, E. E., Heath, N. L., Donahue, J. E. & Stopa, E. G. 2012. Expression of inhibin/activin proteins and receptors in the human hypothalamus and basal forebrain. J Neuroendocrinol, 24, 962-972.
  300. Miller, M. C., Tavares, R., Johanson, C. E., Hovanesian, V., Donahue, J. E., Gonzalez, L., Silverberg, G. D. & Stopa, E. G. 2008. Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease. Brain Res, 1230, 273-280.
  301. Mitchell, M. M., Woods, R., Chi, L. H., Schmidt, R. J., Pessah, I. N., Kostyniak, P. J. & Lasalle, J. M. 2012. Levels of select PCB and PBDE congeners in human postmortem brain reveal possible environmental involvement in 15q11-q13 duplication autism spectrum disorder. Environ Mol Mutagen, 53, 589-598.
  302. Morgan, J. T., Chana, G., Abramson, I., Semendeferi, K., Courchesne, E. & Everall, I. P. 2012. Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain Res, 1456, 72-81.
  303. Morgan, J. T., Chana, G., Pardo, C. A., Achim, C., Semendeferi, K., Buckwalter, J., Courchesne, E. & Everall, I. P. 2010. Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism. Biol Psychiatry, 68, 368-376.
  304. Mukaetova-Ladinska, E. B., Perry, E., Baron, M. & Povey, C. 2012. Ageing in people with autistic spectrum disorder. Int J Geriatr Psychiatry, 27, 109-118.
  305. Mukaetova-Ladinska , E. B., Westwood, J. & Perry, E. K. 2010. Cholinergic component of autism spectrum disorder. In: BLATT, G. J. (ed.) The Neurochemical Basis of Autism: From Molecules to Minicolumns. Berlin: Springer.  129-161.
  306. Mukaetova-Ladinska , E. B., Westwood, J. & Perry, E. K. 2011. Biochemistry of autism: changes in serotonin, reelin and oxytocin. In: ROTH, I. & REZAIE, P. (eds.) Researching the autism spectrum. Contemporary perspectives. Cambridge: Cambridge University Press.
  307. Nasrallah, H. A., Keshavan, M. S., Benes, F. M., Braff, D. L., Green, A. I., Gur, R. E., Kane, J. M., Perkins, D. O., Weiden, P. J., Weinberger, D. R. & Correll, C. U. 2009. Proceedings and data from The Schizophrenia Summit: a critical appraisal to improve the management of Schizophrenia. J Clin Psychiatry, 70 Suppl 1, 4-46.
  308. Naydenov, A.V., Vassoler, F., Luksik, A.S., Kaczmarska, J. & Konradi, C. 2010.  Mitochondrial abnormalities in the putamen in Parkinson’s disease dyskinesia.  Acta Neuropathol,120(5): 623-631
  309. Nguyen, A., Rauch, T. A., Pfeifer, G. P. & Hu, V. W. 2010. Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain. FASEB J, 24, 3036-3051.
  310. Oblak, A., Gibbs, T. T. & Blatt, G. J. 2009. Decreased GABAA receptors and benzodiazepine binding sites in the anterior cingulate cortex in autism. Autism Res, 2, 205-219.
  311. Oblak, A., Kemper, T. L., Bauman, M. L. & Blatt, G. J. 2011a. Cytoarchitectonic abnormalities but normal neuronal and interneuronal densities in the posterior cingulate cortex and fusiform gyrus in autism. Autism Res, 4, 200-211.
  312. Oblak, A. L., Gibbs, T. T. & Blatt, G. J. 2010. Decreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism. J Neurochem, 114, 1414-1423.
  313. Oblak, A. L., Gibbs, T. T. & Blatt, G. J. 2011b. Reduced GABAA receptors and benzodiazepine binding sites in the posterior cingulate cortex and fusiform gyrus in autism. Brain Res, 1380, 218-228.
  314. Oblak, A. L., Rosene, D. L., Kemper, T. L., Bauman, M. L. & Blatt, G. J. 2011c. Altered posterior cingulate cortical cyctoarchitecture, but normal density of neurons and interneurons in the posterior cingulate cortex and fusiform gyrus in autism. Autism Res, 4, 200-211.
  315. Palmieri, L., Papaleo, V., Porcelli, V., Scarcia, P., Gaita, L., Sacco, R., Hager, J., Rousseau, F., Curatolo, P., Manzi, B., Militerni, R., Bravaccio, C., Trillo, S., Schneider, C., Melmed, R., Elia, M., Lenti, C., Saccani, M., Pascucci, T., Puglisi-Allegra, S., Reichelt, K.L. & Persico, A.M.  2010.  Altered calcium homeostasis in autism-spectrum disorders: evidence from biochemical and genetic studies of the mitochondrial aspartate/glutamate carrier AGC1.  Mol Psychiatry, 15:38-52.
  316. Palmieri, L. & Persico, A. M. 2010. Mitochondrial dysfunction in autism spectrum disorders: cause or effect? Biochim Biophys Acta, 1797, 1130-1137.
  317. Pankratz, N., Beecham, G. W., Destefano, A. L., Dawson, T. M., Doheny, K. F., Factor, S. A., Hamza, T. H., Hung, A. Y., Hyman, B. T., Ivinson, A. J., Krainc, D., Latourelle, J. C., Clark, L. N., Marder, K., Martin, E. R., Mayeux, R., Ross, O. A., Scherzer, C. R., Simon, D. K., Tanner, C., Vance, J. M., Wszolek, Z. K., Zabetian, C. P., Myers, R. H., Payami, H., Scott, W. K. & Foroud, T. 2012. Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2. Ann Neurol, 71, 370-384.
  318. Pantazopoulos, H., Murray, E. A. & Berretta, S. 2008. Total number, distribution, and phenotype of cells expressing chondroitin sulfate proteoglycans in the normal human amygdala. Brain Res, 1207, 84-95.
  319. Pantazopoulos, H., Woo, T. U., Lim, M. P., Lange, N. & Berretta, S. 2010. Extracellular matrix-glial abnormalities in the amygdala and entorhinal cortex of subjects diagnosed with schizophrenia. Arch Gen Psychiatry, 67, 155-166.
  320. Park, H., Kam, T. I., Kim, Y., Choi, H., Gwon, Y., Kim, C., Koh, J. Y. & Jung, Y. K. 2012. Neuropathogenic role of adenylate kinase-1 in Abeta-mediated tau phosphorylation via AMPK and GSK3beta. Hum Mol Genet, 21, 2725-2737.
  321. Pearson, B. L., Corley, M. J., Vasconcellos, A., Blanchard, D. C. & Blanchard, R. J. 2013. Heparan sulfate deficiency in postmortem brain tissue from the subventricular zone of the lateral ventricles.  Behav Brain Res, In press.
  322. Pickett, J., Xiu, E., Tuchman, R., Dawson, G. & Lajonchere, C. 2011. Mortality in individuals with autism, with and without epilepsy. J Child Neurol, 26, 932-939.
  323. Pietersen, C. Y., Lim, M. P., Macey, L., Woo, T. U. W. & Sonntag, K. C. 2011. Neuronal type-specific gene expression profiling and laser-capture microdissection. Methods Mol Biol, 755, 327-343.
  324. Pietersen, C. Y., Lim, M. P. & Woo, T. U. W. 2009. Obtaining high quality RNA from single cell populations in human postmortem brain tissue. J Vis Exp(30). pii: 1444.
  325. Podtelezhnikov, A. A., Tanis, K. Q., Nebozhyn, M., Ray, W. J., Stone, D. J. & Loboda, A. P. 2011. Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging. PLoS One, 6, e29610.
  326. Prasad, K., Beach, T. G., Hedreen, J. & Richfield, E. K. 2012. Critical role of truncated alpha-synuclein and aggregates in Parkinson's disease and incidental Lewy body disease. Brain Pathol, 22, 811-825.
  327. Ramos, E. M., Latourelle, J. C., Lee, J. H., Gillis, T., Mysore, J. S., Squitieri, F., Di Pardo, A., Di Donato, S., Hayden, M. R., Morrison, P. J., Nance, M., Ross, C. A., Margolis, R. L., Gomez-Tortosa, E., Ayuso, C., Suchowersky, O., Trent, R. J., Mccusker, E., Novelletto, A., Frontali, M., Jones, R., Ashizawa, T., Frank, S., Saint-Hilaire, M. H., Hersch, S. M., Rosas, H. D., Lucente, D., Harrison, M. B., Zanko, A., Marder, K., Gusella, J. F., Lee, J. M., Alonso, I., Sequeiros, J., Myers, R. H. & Macdonald, M. E. 2012. Population stratification may bias analysis of PGC-1alpha as a modifier of age at Huntington disease motor onset. Hum Genet, 131, 1833-1840.
  328. Rao, J.S., Keleshian, V.L., Klein, S., & Rapoport, S.I.  2012.  Epigenetic modifications in frontal cortex from Alzheimer’s disease and bipolar disorder patients.  Transl Psychiatry3:e132.
  329. Rao, J.S, Kellom, M., Reese, E.A., Rapoport, S.I. & Kim, H.W.  2012.  Dysregulated glutamate and dopamine transporters in postmortem frontal cortex from bipolar and schizophrenic patients.  J Affect Disord, 136(1-2):63-71.
  330. Rao, J.S., Rapoport, S.I., & Kim, H.W.  2011.  Altered neuroinflammatory, arachidonic acid cascade and synaptic markers in postmortem Alzheimer’s disease brain.  Transl Psychiatry, 1:e31.
  331. Rao, J.S., Harry, G.J., Rapoport, S.I. & Kim HW.  2010.  Increased excitotoxicity andneuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients. Mol. Psychiatry, 15(4):384-92.
  332. Rao, J.S., Rapoport, S.I., & Kim, H.W.  2009.  Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients.  Int J Neuropsychopharmaco, 12(6):851-60.
  333. Rao, M. V., Mohan, P. S., Peterhoff, C. M., Yang, D. S., Schmidt, S. D., Stavrides, P. H., Campbell, J., Chen, Y., Jiang, Y., Paskevich, P. A., Cataldo, A. M., Haroutunian, V. & Nixon, R. A. 2008. Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression. J Neurosci, 28, 12241-12254.
  334. Ray, B., Long, J. M., Sokol, D. K. & Lahiri, D. K. 2011. Increased secreted amyloid precursor protein-alpha (sAPPalpha) in severe autism: proposal of a specific, anabolic pathway and putative biomarker. PLoS One, 6, e20405.
  335. Reiner, A., Wang, H. B., Del Mar, N., Sakata, K., Yoo, W. & Deng, Y. P. 2012. BDNF may play a differential role in the protective effect of the mGluR2/3 agonist LY379268 on striatal projection neurons in R6/2 Huntington's disease mice. Brain Res, 1473, 161-172.
  336. Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E. & James, S. J. 2012. Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain. Transl Psychiatry, 2, e134.
  337. Rousseau, E., Kojima, R., Hoffner, G., Djian, P. & Bertolotti, A. 2009. Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones. J Biol Chem, 284, 1917-1929.
  338. Roybon, L., Hjalt, T., Stott, S., Guillemot, F., Li, J. Y. & Brundin, P. 2009. Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis. PLoS One, 4, e4779.
  339. Sajdel-Sulkowska, E. M., Lipinski, M., Windom, H., Audhya, T. & Mcginnis, W. 2008. Oxidative Stress in Autism: Elevated Cerebellar 3-nitrotyrosine Levels. Am J Biochem Biotech, 4, 73-84.
  340. Santos, M., Uppal, N., Butti, C., Wicinski, B., Schmeidler, J., Giannakopoulos, P., Heinsen, H., Schmitz, C. & Hof, P. R. 2011. Von Economo neurons in autism: a stereologic study of the frontoinsular cortex in children. Brain Res, 1380, 206-217.
  341. Sarachana, T., Xu, M., Wu, R. C. & Hu, V. W. 2011. Sex hormones in autism: androgens and estrogens differentially and reciprocally regulate RORA, a novel candidate gene for autism. PLoS One, 6, e17116.
  342. Sarachana, T., Zhou, R., Chen, G., Manji, H. K. & Hu, V. W. 2010. Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines. Genome Med, 2, 23.
  343. Scherzer, C. R., Grass, J. A., Liao, Z., Pepivani, I., Zheng, B., Eklund, A. C., Ney, P. A., Ng, J., Mcgoldrick, M., Mollenhauer, B., Bresnick, E. H. & Schlossmacher, M. G. 2008. GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein. Proc Natl Acad Sci U S A,105, 10907-10912.
  344. Schmidt, S. D., Mazzella, M. J., Nixon, R. A. & Mathews, P. M. 2012a. Abeta measurement by enzyme-linked immunosorbent assay. Methods Mol Biol, 849, 507-527.
  345. Schmidt, S. D., Nixon, R. A. & Mathews, P. M. 2012b. Tissue processing prior to analysis of Alzheimer's disease associated proteins and metabolites, including Abeta. Methods Mol Biol, 849, 493-506.
  346. Schmitz, C. & Rezaie, P. 2008. The neuropathology of autism: where do we stand? Neuropathol Appl Neurobiol, 34, 4-11.
  347. Schroeder, D. I., Lott, P., Korf, I. & Lasalle, J. M. 2011. Large-scale methylation domains mark a functional subset of neuronally expressed genes. Genome Res, 21, 1583-1591.
  348. Schumann, C. M. & Nordahl, C. W. 2011. Bridging the gap between MRI and postmortem research in autism. Brain Res, 1380, 175-186.
  349. Sheng, G., Demers, M., Subburaju, S. & Benes, F. M. 2012. Differences in the circuitry-based association of copy numbers and gene expression between the hippocampi of patients with schizophrenia and the hippocampi of patients with bipolar disorder. Arch Gen Psychiatry, 69, 550-561.
  350. Shulha, H. P., Cheung, I., Whittle, C., Wang, J., Virgil, D., Lin, C. L., Guo, Y., Lessard, A., Akbarian, S. & Weng, Z. 2012. Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons. Arch Gen Psychiatry, 69, 314-324.
  351. Siddiqui, A., Rivera-Sanchez, S., Castro Mdel, R., Acevedo-Torres, K., Rane, A., Torres-Ramos, C. A., Nicholls, D. G., Andersen, J. K. & Ayala-Torres, S. 2012. Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease. Free Radic Biol Med, 53, 1478-1488.
  352. Simms, M. L., Kemper, T. L., Timbie, C. M., Bauman, M. L. & Blatt, G. J. 2009. The anterior cingulate cortex in autism: heterogeneity of qualitative and quantitative cytoarchitectonic features suggests possible subgroups. Acta Neuropathol, 118, 673-684.
  353. Simunovic, F., Yi, M., Wang, Y., Macey, L., Brown, L. T., Krichevsky, A. M., Andersen, S. L., Stephens, R. M., Benes, F. M. & Sonntag, K. C. 2009. Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology. Brain, 132, 1795-1809.
  354. Simunovic, F., Yi, M., Wang, Y., Stephens, R. & Sonntag, K. C. 2010. Evidence for gender-specific transcriptional profiles of nigral dopamine neurons in Parkinson disease. PLoS One, 5, e8856.
  355. Skafidas, E., Testa, R., Zantomio, D., Chana, G., Everall, I. P. & Pantelis, C. 2012. Predicting the diagnosis of autism spectrum disorder using gene pathway analysis. Mol Psychiatry.
  356. Sonntag, K. C. 2010. MicroRNAs and deregulated gene expression networks in neurodegeneration. Brain Res, 1338, 48-57.
  357. Sonntag, K. C. & Wahlestedt, C. 2010. RNA mechanisms in CNS systems and disorders. Brain Res, 1338, 1-2.
  358. Sonntag, K. C., Woo, T. U. W. & Krichevsky, A. M. 2012. Converging miRNA functions in diverse brain disorders: a case for miR-124 and miR-126. Exp Neurol, 235, 427-435.
  359. Stopa, E. G., Butala, P., Salloway, S., Johanson, C. E., Gonzalez, L., Tavares, R., Hovanesian, V., Hulette, C. M., Vitek, M. P. & Cohen, R. A. 2008. Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype. Stroke, 39, 814-821.
  360. Sokol, D.K., Maloney, B., Long, J.M., Ray, B. & Lahiri, D.K.  2011.  Autism, Alzheimer disease and gragile X.  APP, FMRP and MGluR5 are molecular Links.  Neurology, 76(15):1344-52.
  361. Swami, M., Hendricks, A. E., Gillis, T., Massood, T., Mysore, J., Myers, R. H. & Wheeler, V. C. 2009. Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset. Hum Mol Genet, 18, 3039-3047.
  362. Szymanski, M., Wang, R., Bassett, S. S. & Avramopoulos, D. 2011. Alzheimer's risk variants in the clusterin gene are associated with alternative splicing. Transl Psychiatry, 1.
  363. Tang, B., Dean, B. & Thomas, E. A. 2011. Disease- and age-related changes in histone acetylation at gene promoters in psychiatric disorders. Transl Psychiatry, 1, e64.
  364. Tobin, J. E., Latourelle, J. C., Lew, M. F., Klein, C., Suchowersky, O., Shill, H. A., Golbe, L. I., Mark, M. H., Growdon, J. H., Wooten, G. F., Racette, B. A., Perlmutter, J. S., Watts, R., Guttman, M., Baker, K. B., Goldwurm, S., Pezzoli, G., Singer, C., Saint-Hilaire, M. H., Hendricks, A. E., Williamson, S., Nagle, M. W., Wilk, J. B., Massood, T., Laramie, J. M., Destefano, A. L., Litvan, I., Nicholson, G., Corbett, A., Isaacson, S., Burn, D. J., Chinnery, P. F., Pramstaller, P. P., Sherman, S., Al-Hinti, J., Drasby, E., Nance, M., Moller, A. T., Ostergaard, K., Roxburgh, R., Snow, B., Slevin, J. T., Cambi, F., Gusella, J. F. & Myers, R. H. 2008. Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology, 71, 28-34.
  365. Tsuyoshi, F., Kim, M., Lipinski, M., Li, J., Kim, D, Lu, T., Shen, Y., Rameh, L., Yankner, B, Tsai L. & Yuan, J.  2010.  Negative Regulation of Vps34 by Cdk Mediated Phosphorylation.  Molecular Cell, 38, 500-511.
  366. Van Kooten, I. A., Palmen, S. J., Von Cappeln, P., Steinbusch, H. W., Korr, H., Heinsen, H., Hof, P. R., Van Engeland, H. & Schmitz, C. 2008. Neurons in the fusiform gyrus are fewer and smaller in autism. Brain, 131, 987-999.
  367. Voineagu, I., Wang, X., Johnston, P., Lowe, J. K., Tian, Y., Horvath, S., Mill, J., Cantor, R. M., Blencowe, B. J. & Geschwind, D. H. 2011. Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature, 474, 380-384.
  368. Wang, A. Y., Lohmann, K. M., Yang, C. K., Zimmerman, E. I., Pantazopoulos, H., Herring, N., Berretta, S., Heckers, S. & Konradi, C. 2011. Bipolar disorder type 1 and schizophrenia are accompanied by decreased density of parvalbumin- and somatostatin-positive interneurons in the parahippocampal region. Acta Neuropathol, 122, 615-626.
  369. Wegiel, J., Frackowiak, J., Mazur-Kolecka, B., Schanen, N. C., Cook, E. H., Jr., Sigman, M., Brown, W. T., Kuchna, I., Wegiel, J., Nowicki, K., Imaki, H., Ma, S. Y., Chauhan, A., Chauhan, V., Miller, D. L., Mehta, P. D., Flory, M., Cohen, I. L., London, E., Reisberg, B., De Leon, M. J. & Wisniewski, T. 2012a. Abnormal intracellular accumulation and extracellular Abeta deposition in idiopathic and Dup15q11.2-q13 autism spectrum disorders. PLoS One, 7, e35414.
  370. Wegiel, J., Kuchna, I., Nowicki, K., Imaki, H., Wegiel, J., Marchi, E., Ma, S. Y., Chauhan, A., Chauhan, V., Bobrowicz, T. W., De Leon, M., Louis, L. A., Cohen, I. L., London, E., Brown, W. T. & Wisniewski, T. 2010a. The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. Acta Neuropathol, 119, 755-770.
  371. Wegiel, J., Lightfoot, D., Pickett, J. & Brown, W. T. 2012b. New trends in brain and tissue banking for autism research.  Aut Spec Disord, 7, 1-27.
  372. Wegiel, J., Schanen, N. C., Cook, E. H., Brown, W. T., Kuchna, I., Nowicki, K., Wegiel, H., Imaki, H., London, E. & Wisniewski, H. 2012c. Clinicopathological stratification of idiopathic autism and autism associated with duplications 15q11.2-q13. In: HOF, P. R. & BUXBAUM, J. D. (eds.) Neuroscience of autism spectrum disorders. New York: Academic Press.
  373. Wegiel, J., Schanen, N. C., Cook, E. H., Sigman, M., Brown, W. T., Kuchna, I., Nowicki, K., Wegiel, J., Imaki, H., Ma, S. Y., Marchi, E., Wierzba-Bobrowicz, T., Chauhan, A., Chauhan, V., Cohen, I. L., London, E., Flory, M., Lach, B. & Wisniewski, T. 2012d. Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autism. J Neuropathol Exp Neurol, 71, 382-397.
  374. Wegiel, J., Wisniewski, H., Chauhan, A., Chauhan, V., Kuchna, I., Nowicki, K., Imaki, H., Ma, S. Y., Wierzba-Bobrowicz, T., Cohen, I. L., London, E. & Brown, W. T. 2010b. Type, topography, and sequelae of neuropathological changes shaping clinical phenotype of autism. In: CHAUHAN, A., CHAUHAN, V. & BROWN, W. T. (eds.) Autism. Oxidative stress, inflammation, and immune abnormalities. Boca Raton: CRC Press, Taylor and Francis Group.
  375. Wegiel, J., Wisniewski, H. M., Dziewiatkowski, J., Badmajew, E., Tarnawski, M., Reisberg, B., Mlodzik, B., De Leon, M. J. & Miller, D. C. 1999. Cerebellar atrophy in Alzheimer's disease-clinicopathological correlations. Brain Res, 818, 41-50.
  376. Weidenheim, K. M., Dickson, D. W. & Rapin, I. 2009. Neuropathology of Cockayne syndrome: Evidence for impaired development, premature aging, and neurodegeneration. Mech Ageing Dev, 130, 619-636.
  377. Weidenheim, K. M., Escobar, A. & Rapin, I. 2012. Brief report: life history and neuropathology of a gifted man with Asperger syndrome. J Autism Dev Disord, 42, 460-467.
  378. Weiss, L. A., Arking, D. E., Daly, M. J. & Chakravarti, A. 2009. A genome-wide linkage and association scan reveals novel loci for autism. Nature, 461, 802-808.
  379. Whitney, E. R., Kemper, T. L., Bauman, M. L., Rosene, D. L. & Blatt, G. J. 2008a. Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains: a stereological experiment using calbindin-D28k. Cerebellum, 7, 406-416.
  380. Whitney, E. R., Kemper, T. L., Rosene, D. L., Bauman, M. L. & Blatt, G. J. 2008b. Calbindin-D28k is a more reliable marker of human Purkinje cells than standard Nissl stains: a stereological experiment. J Neurosci Methods, 168, 42-47.
  381. Whitney, E. R., Kemper, T. L., Rosene, D. L., Bauman, M. L. & Blatt, G. J. 2009. Density of cerebellar basket and stellate cells in autism: evidence for a late developmental loss of Purkinje cells. J Neurosci Res, 87, 2245-2254.
  382. Williams, E. L. & Casanova, M. F. 2010. Autism and dyslexia: a spectrum of cognitive styles as defined by minicolumnar morphometry. Med Hypotheses, 74, 59-62.
  383. Wintle, R. F., Lionel, A. C., Hu, P., Ginsberg, S. D., Pinto, D., Thiruvahindrapduram, B., Wei, J., Marshall, C. R., Pickett, J., Cook, E. H. & Scherer, S. W. 2011. A genotype resource for postmortem brain samples from the Autism Tissue Program. Autism Res, 4, 89-97.
  384. Wolfe, D. M. & Nixon, R. A. 2012. Autophagy failure in Alzheimer’s disease and lysosomal storage disorders: A common pathway to neurodegeneration. In: YUE, Z. & CHU, C. T. (eds.) Autophagy of the nervous system: Cellular self-digestion in neurons and neurological diseases. Hackensack, New Jersey: World Scientific Publishing
  385. Woo, T. U. W., Kim, A. M. & Viscidi, E. 2008a. Disease-specific alterations in glutamatergic neurotransmission on inhibitory interneurons in the prefrontal cortex in schizophrenia. Brain Res, 1218, 267-277.
  386. Woo, T. U. W., Shrestha, K., Lamb, D., Minns, M. M. & Benes, F. M. 2008b. N-methyl-D-aspartate receptor and calbindin-containing neurons in the anterior cingulate cortex in schizophrenia and bipolar disorder. Biol Psychiatry, 64, 803-809.
  387. Woo, T. U. W., Spencer, K. & Mccarley, R. W. 2010. Gamma oscillation deficits and the onset and early progression of schizophrenia. Harv Rev Psychiatry, 18, 173-189.
  388. Xiong, L., Catoire, H., Dion, P., Gaspar, C., Lafreniere, R. G., Girard, S. L., Levchenko, A., Riviere, J. B., Fiori, L., St-Onge, J., Bachand, I., Thibodeau, P., Allen, R., Earley, C., Turecki, G., Montplaisir, J. & Rouleau, G. A. 2009. MEIS1 intronic risk haplotype associated with restless legs syndrome affects its mRNA and protein expression levels. Hum Mol Genet, 18, 1065-1074.
  389. Yasui, D. H., Scoles, H. A., Horike, S., Meguro-Horike, M., Dunaway, K. W., Schroeder, D. I. & Lasalle, J. M. 2011. 15q11.2-13.3 chromatin analysis reveals epigenetic regulation of CHRNA7 with deficiencies in Rett and autism brain. Hum Mol Genet, 20, 4311-4323.
  390. Yip, J., Soghomonian, J. J. & Blatt, G. J. 2008. Increased GAD67 mRNA expression in cerebellar interneurons in autism: implications for Purkinje cell dysfunction. J Neurosci Res, 86, 525-530.
  391. Yip, J., Soghomonian, J. J. & Blatt, G. J. 2009. Decreased GAD65 mRNA levels in select subpopulations of neurons in the cerebellar dentate nuclei in autism: an in situ hybridization study. Autism Res, 2, 50-59.
  392. Young, A. M., Campbell, E., Lynch, S., Suckling, J. & Powis, S. J. 2011. Aberrant NF-kappaB expression in autism spectrum condition: a mechanism for neuroinflammation. Front Psychiatry, 2, 27.
  393. Zheng, B., Liao, Z., Locascio, J. J., Lesniak, K. A., Roderick, S. S., Watt, M. L., Eklund, A. C., Zhang-James, Y., Kim, P. D., Hauser, M. A., Grunblatt, E., Moran, L. B., Mandel, S. A., Riederer, P., Miller, R. M., Federoff, H. J., Wullner, U., Papapetropoulos, S., Youdim, M. B., Cantuti-Castelvetri, I., Young, A. B., Vance, J. M., Davis, R. L., Hedreen, J. C., Adler, C. H., Beach, T. G., Graeber, M. B., Middleton, F. A., Rochet, J. C. & Scherzer, C. R. 2010. PGC-1alpha, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med, 2, 52ra73.
  394. Zhubi, A., Veldic, M., Puri, N. V., Kadriu, B., Caruncho, H., Loza, I., Sershen, H., Lajtha, A., Smith, R. C., Guidotti, A., Davis, J. M. & Costa, E. 2009. An upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes. Schizophr Res,111, 115-122.
  395. Zikopoulos, B. & Barbas, H. 2010. Changes in prefrontal axons may disrupt the network in autism. J Neurosci, 30, 14595-14609.
Modified:  18-Feb-2014